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Cureus
November 2024
Neuroradiology Department, Unidade Local de Saúde de São João, Porto, PRT.
Bone or cartilage anomalies affecting the arteries supplying the brain can be a structural cause of ischemic stroke. Due to their rarity, there is currently no standardized approach for evaluating and treating these so-called bony strokes. We present a case of a 79-year-old woman with a history of cranial settling due to rheumatoid arthritis (RA) and moderate disability, who presented with insidious dizziness and gait disturbances over three weeks.
View Article and Find Full Text PDFEur J Neurol
January 2025
Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Biomedical Research Institute, Busan, South Korea.
Background And Purpose: The dorsolateral portion of the caudal pons contains the vestibular nucleus (VN) and inferior cerebellar peduncle (ICP) that play important roles in conveying and processing vestibular and ocular motor signals. This study aimed to characterize ocular motor abnormalities along with their anatomical correlations in dorsolateral pons (DLP) lesions.
Methods: We analyzed clinical features, and results of neuro-otological evaluations and neuroimaging of 18 patients with unilateral DLP lesions (17 with DLP infarction and 1 with cavernous malformation) from among 506 patients with pontine infarction in a stroke registry.
Clin Pract Cases Emerg Med
November 2024
University of Louisville Health, Louisville, Kentucky.
Introduction: Fahr disease and Fahr syndrome represent clinical entities that result in diffuse intracranial brain calcification, either by way of genetic mutation in the case of the former or by secondary endocrine dysfunction in the latter.
Case Report: We present a case of a middle-aged male with undiagnosed Fahr syndrome, identified during evaluation for symptoms of an acute posterior circulation cerebrovascular accident.
Conclusion: Fahr syndrome is a clinical constellation of symptoms and radiographic findings often seen in late-stage hypoparathyroidism.
Front Pharmacol
December 2024
Department of Experimental Animal Center, Xuanwu Hospital of Capital Medical University, Beijing Municipal Geriatric Medical Research Center, Beijing, China.
Background And Objective: Until now, there has been an unmet need for treatments promoting chronic-phase post-stroke functional recovery. We previously found that morroniside promoted endogenous neurogenesis in ischemic stroke, but its therapeutic window was limited to the first 48 h. Here, we aimed to explore whether deep brain stimulation (DBS) combined with morroniside could enhance neurogenesis in rats subjected to focal ischemic stroke and contributes to functional recovery.
View Article and Find Full Text PDFCureus
December 2024
Department of Radiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.
Bilateral middle cerebellar peduncle (MCP) infarction is a rare manifestation of ischemic stroke. We report a middle-aged male patient who presented with acute onset of vertigo, left ear deafness, and severe ataxia. Magnetic resonance imaging (MRI) of the brain confirmed the presence of infarction in the bilateral middle cerebellar peduncles due to stenosis of the posterior circulation arteries.
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