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Effects of high-frequency repetitive transcranial magnetic stimulation of affected hemisphere on motor recovery in patients in the acute stage of ischemic stroke: Preliminary results .
Neuro Endocrinol Lett
December 2024
1st Department of Neurology, Faculty of Medicine, Comenius University, Bratislava, Slovakia Rehabilitation Centre Harmony, Bratislava, Slovakia.
Objectives: Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neurostimulation technique that uses magnetic field to comprehensively influence events in the brain. Its use in patients after stroke focuses mainly on influencing brain neuroplasticity and therefore has the potential to improve motor functions in these patients. This study investigates the effect of rTMS on motor function recovery in patients in the acute stage of ischemic stroke.
View Article and Find Full Text PDFCytidine analogs in plant epigenetic research and beyond.
J Exp Bot
December 2024
Centre of Plant Structural and Functional Genomics, Institute of Experimental Botany, Czech Acad Sci, Šlechtitelů 31, Olomouc 77900, Czech Republic.
Cytosine (DNA) methylation plays important roles in silencing transposable elements, plant development, genomic imprinting, stress responses, and maintenance of genome stability. To better understand the functions of this epigenetic modification, several tools have been developed to manipulate DNA methylation levels. These include mutants of DNA methylation writers and readers, targeted manipulation of locus-specific methylation, and the use of chemical inhibitors.
View Article and Find Full Text PDF[Advances in the application of comprehensive behavioral intervention in tic disorder].
Zhongguo Dang Dai Er Ke Za Zhi
December 2024
Department of Pediatrics, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Tic disorder is a neurodevelopmental disorder that occurs in children or adolescents, often attracting the attention of others due to involuntary, repetitive, and non-rhythmic tics, and drug therapy often causes negative emotions in children and their families due to its significant adverse reactions, poor compliance, and tendency of recurrence after drug withdrawal. In recent years, comprehensive behavioral intervention has shown great potential as a safe and effective treatment modality for tic disorders, with few adverse reactions. This article reviews the advances in the application of comprehensive behavioral intervention for tic disorder in China and abroad in the past 5 years, in order to provide a reference for clinical application.
View Article and Find Full Text PDFThird generation sequencing transforming plant genome research: Current trends and challenges.
Gene
December 2024
Department of Molecular Biology and Biotechnology, Cotton University, Panbazar, Guwahati, Assam 781001, India. Electronic address:
In recent years, third-generation sequencing (TGS) technologies have transformed genomics and transcriptomics research, providing novel opportunities for significant discoveries. The long-read sequencing platforms, with their unique advantages over next-generation sequencing (NGS), including a definitive protocol, reduced operational time, and real-time sequencing, possess the potential to transform plant genomics. TGS optimizes and enhances the efficiency of data analysis by removing the necessity for time-consuming assembly tools.
View Article and Find Full Text PDFChallenges in Describing Tremor and Dystonia.
Neurology
January 2025
Departments of Neurology, Human Genetics and Pediatrics, Emory University, Atlanta, GA.
Tremor is defined as an oscillatory and rhythmical movement. By contrast, dystonia is defined by sustained or intermittent abnormal postures, repetitive movements, or both. Tremor and dystonia often coexist in the same individual.
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