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Dataset for the role of sustained attention in memory formation of transgenic mice for Alzheimer׳s disease. | LitMetric

Dataset for the role of sustained attention in memory formation of transgenic mice for Alzheimer׳s disease.

Data Brief

Graduate Course on Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil; School of Arts, Sciences and Humanities, University of Sao Paulo, Sao Paulo, Brazil.

Published: March 2016

Weekly submission of rats to active avoidance apparatus can be considered a neurostimulation strategy, once it can improve memory and can increase the density of receptors from different neurotransmitter systems in brain areas related to memory. These benefits were observed in rats chronically infused with amyloid-β peptide. In the present work it is presented that the same benefit for memory was observed in five months old transgenic mice for Alzheimer's disease (TG-PDGFB-APPSw,Ind). However, at this age, no change in density of nicotinic receptors was observed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744239PMC
http://dx.doi.org/10.1016/j.dib.2016.01.015DOI Listing

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