Enhanced-Resolution Optical Coherence Tomography Imaging.

Purpose: The effect of the enhanced-resolution imaging (ERI) technique on optical coherence tomography (OCT) images was evaluated.

Methods: A total of 5 healthy subjects and 20 patients diagnosed with various eye diseases were recruited into the study. ERI, a novel image processing technique, was accomplished by using super-resolution technology, and was assessed by objectively and subjectively comparing the image quality among three different image groups: images enlarged without bicubic interpolation (NONE), with bicubic interpolation (IP), and with ERI.

Results: ERI showed a higher ratio of the detailed variance to the background variance than NONE, whereas no significant difference was detected between NONE and IP. The mean opinion score of 5 experienced retinal specialists for ERI was significantly higher than that for IP.

Conclusions: ERI generated a sharper image and clearly visualized small objects. Additionally, it is effective in enhancing OCT image quality.