AI Article Synopsis
- Triazolinediones (TADs) are versatile reagents in organic synthesis with applications in fields like polymer science and click chemistry.
- This review presents two case studies showcasing TADs' synthetic capabilities and addresses the challenges due to their limited availability.
- It aims to guide researchers on the synthesis, reactivity, and potential uses of TADs, encouraging further exploration of their unique properties.
Article Abstract
Triazolinediones (TADs) are unique reagents in organic synthesis that have also found wide applications in different research disciplines, in spite of their somewhat "exotic" reputation. In this review, we offer two case studies that demonstrate the possibilities of these versatile and reliable synthetic tools, namely, in the field of polymer science as well as in more recently emerging applications in the field of click chemistry. As the general use of triazolinediones has always been hampered by the limited commercial and synthetic availability of such reagents, we also offer a review of the available TAD reagents, together with a detailed discussion of their synthesis and reactivity. This review thus aims to serve as a practical guide for researchers that are interested in exploiting and further developing the exceptional click-like reactivity of triazolinediones in various applications.
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