Background/aims: To investigate the clinicopathological parameters influencing assessment of FDG SPECT in gastric cancer.
Methodology: The frames of FDG SPECT and clinical data of 105 patients with gastric cancer were collected. The univariate and multivariate analyses were performed to assess the relationship between the visual assessment, SUV(max) and clinicopathological parameters.
Results: There were statistically significant in tumor size and pT stage between the positive and negative group (p < 0.01), while there was no statistically significant in gender, age, tumor localization, pN stage, histological type, adenocarcinoma differentiation (p > 0.05). Tumor size and pT stage were independent factors associated with visual assessment at multivariate analyses (p < 0.05). SUV(max) was positively correlated with age, tumor size and pT stage, respectively (p < 0.01). There was no statistically significant of SUV(max) in gender, tumor localization, pN stage, histological type, adenocarcinoma differentiation (p > 0.05). Age, tumor size and pT stage were independent factors related to SUV(max) (p < 0.05).
Conclusions: Tumor size and depth of invasion were clinicopathological parameters influencing FDG SPECT assessment in gastric cancer independently. The relationship between tumor size, depth of invasion, expression of GLUT-1 and FDG imaging should be determined by further research.
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