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OPTIMIZING PERIOPERATIVE CARE FOR PERIHILAR CHOLANGIOCARCINOMA: THE CRUCIAL ROLE OF MULTIDISCIPLINARY MANAGEMENT, NEOADJUVANT THERAPY, AND INTERVENTIONAL RADIOLOGY.
Arq Bras Cir Dig
January 2025
Pontificia Universidad Católica de Chile, Department of Digestive Surgery - Santiago, Chile.
Background: Perihilar cholangiocarcinoma presents unique challenges in perioperative management, requiring a comprehensive approach to optimize patient outcomes.
Aims: This case study focuses on the multidisciplinary management and innovative interventions performed in the perioperative care of a patient with hilar cholangiocarcinoma.
Methods: A comprehensive assessment and treatment strategy involving neoadjuvant therapy and interventional radiology techniques were implemented.
Altered microbiome and metabolome profiling in fearful companion dogs: An exploratory study.
PLoS One
January 2025
Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Behavioral dysfunctions in dogs represent one of the main social concerns, since they can endanger animals and human-dog relationship. Together with the trigger stimulus (human, animal, place, scent, auditory stimuli, objects), dogs can experience stressful conditions, either in multiple settings or unique situations, more often turning into generalized fear. Such a dysfunctional behavior can be associated with genetic susceptibility, environmental factors, traumatic experiences, and medical conditions.
View Article and Find Full Text PDFPatient Complexity, Social Factors, and Hospitalization Outcomes at Academic and Community Hospitals.
JAMA Netw Open
January 2025
Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.
Importance: There have been limited evaluations of the patients treated at academic and community hospitals. Understanding differences between academic and community hospitals has relevance for the design of clinical models of care, remuneration for clinical services, and health professional training programs.
Objective: To evaluate differences in complexity and clinical outcomes between patients admitted to general medical wards at academic and community hospitals.
Purpose Of Review: The 2024 mpox outbreak, primarily driven by the possibly more virulent clade Ib strain, prompted the WHO declaring it a public health emergency of international concern (PHEIC) on August 14, 2024. This review provides essential guidance for clinicians managing mpox cases, as it contrasts the features of the 2024 outbreak with those of the 2022 epidemic to support better clinical decision-making.
Recent Findings: The review highlights significant differences between the 2024 and 2022 outbreaks, including total case numbers, demographic distribution, and fatality rates.
Monitoring changes and multi-scenario simulations of land use and ecosystem service values in coastal cities: A case study of Qingdao, China.
Environ Monit Assess
January 2025
Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, 100101, China.
The study of land cover dynamics and the valuation of ecosystem services in coastal cities is pivotal for guiding sustainable urban development and conserving natural resources amidst the unique challenges posed by their geographical and ecological contexts. This study utilizes a 30 m × 30 m land use/cover change (LUCC) dataset to elucidate the spatiotemporal evolution of LUCC and ecosystem service value (ESV) and the trade-offs and synergistic relationships among ecosystem services in the coastal city of Qingdao under three different scenarios over the past 35 years and in the future based on the dual perspective of the past-future by using the equivalent factor approach (EFA), the PLUS model, and Spearman's rank correlation coefficient. The findings reveal a pronounced expansion in built-up areas in Qingdao from 1985 to 2020, with a concomitant significant reduction in cropland, leading to a fluctuation in the total ESV, which initially increased and then declined.
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