Air pollution exposure has been linked to numerous adverse health effects, with some disadvantaged subgroups disproportionately burdened. The objective of this work was to characterize distributions of emissions and concentrations of a few important urban air toxics at high spatiotemporal resolution in order to assess exposure and inequality. Benzene, 1,3-butadiene, formaldehyde, and acetaldehyde were the focus pollutants, with oxides of nitrogen (NOx) estimated for comparisons. Primary pollutant emissions were estimated for the full spectrum of source types in the Tampa area using a hybrid approach that is most detailed for major roadways and includes hourly variations in vehicle speed. Resultant pollutant concentrations were calculated using the CALPUFF dispersion model, and combined with CMAQ model output to account for secondary formation of formaldehyde and acetaldehyde. Census demographic data were applied to estimate residential pollution exposures and inequality among population subgroups. Estimated concentrations of benzene, 1,3-butadiene, and NOx were generally higher in urban areas and lower in rural areas. Exposures to these pollutants were disproportionately high for subgroups characterized as black, Hispanic and low income (annual household income less than $20,000). For formaldehyde and acetaldehyde, the patterns of concentration and exposure were largely reversed. Results suggest that disparities in exposure depend on pollutant type.
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http://dx.doi.org/10.1016/j.scitotenv.2016.01.157 | DOI Listing |
J Chem Phys
January 2025
Fritz Haber Research Center for Molecular Dynamics, The Hebrew University of Jerusalem, Jerusalem 9190401, Israel.
Complex organic molecules are widespread in different areas of the interstellar medium, including cold areas, such as molecular clouds, where chemical reactions occur in ice. Among the observed molecules are oxygen-bearing organic molecules, which are of high interest given their significant role in astrobiology. Despite the observed rich chemistry, the underlying molecular mechanisms responsible for molecular formation in such cold dilute areas are still not fully understood.
View Article and Find Full Text PDFDiscov Med
December 2024
Department of Biological Hematology, Tours University Hospital, 37000 Tours, France.
Aldehyde dehydrogenases (ALDHs) constitute a group of enzymes that catalyze the oxidation of aldehydes to carboxylic acids. The human ALDH superfamily, including 19 different isoenzymes (ALDH1A1, ALDH1A2, ALDH1A3, AHDH1B1, ALDH1L1, ALDH1L2, ALDH2, ALDH3A1, ALDH3A2, ALDH3B1, ALDH3B2, ALDH4A1, ALDH5A1, ALDH6A1, ALDH7A1, ALDH8A1, ALDH9A1, ALDHA16A1, ALDH18A1), displays different key physiological and toxicological functions, with specific tissue expression and substrate specificity. Several studies have established that ALDH are interesting markers for the identification and quantification of human hematopoietic stem cells and cancer stem cells, notably leukemic stem cells.
View Article and Find Full Text PDFMolecules
December 2024
School of Basic Medical Sciences/School of Biology and Engineering, Guizhou Medical University, Guiyang 550025, China.
Chalcogen bonds (ChBs) involving selenium have attracted substantial scholarly interest in past years owing to their fundamental roles in various chemical and biological fields. However, the effect of the valency state of the electron-deficient selenium atom on the characteristics of such ChBs remains unexplored. Herein, we comparatively studied the σ-hole-type Se∙∙∙O ChBs between SeF/SeF and a series of oxygen-bearing Lewis bases, including water, methanol, dimethyl ether, ethylene oxide, formaldehyde, acetaldehyde, acetone, and formic acid, using ab initio computations.
View Article and Find Full Text PDFMolecules
November 2024
Department of Chemistry and Biochemistry & Advanced Materials and Liquid Crystal Institute, Kent State University, Kent, OH 44242, USA.
Emissions of volatile organic compounds (VOCs) such as benzene, toluene, xylene, styrene, hexane, tetrachloroethylene, acetone, acetaldehyde, formaldehyde, isopropanol, etc., increase dramatically with accelerated industrialization and economic growth. Most VOCs cause serious environmental pollution and threaten human health due to their toxic and carcinogenic nature.
View Article and Find Full Text PDFChem Res Toxicol
December 2024
Office of Science, Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, Maryland 20993, United States.
Nicotine salt e-liquids are widely used in pod-style and disposable electronic nicotine delivery systems (ENDS). Studying the physical and chemical properties of their emissions can inform their toxicological impact. A prior companion study reported the harmful and potentially harmful constituents (HPHCs) and aerosol particle sizes produced from laboratory-made nicotine salt and freebase nicotine e-liquids to assess the effects of varying nicotine salts and nicotine protonation.
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