Aim: The aim of this study was to examine the relationship between ventilatory adaptation and performance during altitude training at 2700 m.
Methods: Seven elite cyclists (age: 21.2 ± 1.1 yr, body mass: 69.9 ± 5.6 kg, height 176.3 ± 4.9 cm) participated in this study. A hypoxic ventilatory response (HVR) test and a submaximal exercise test were performed at sea level prior to the training camp and again after 15 d at altitude (ALT15). Ventilation (VE), end-tidal carbon-dioxide partial pressure (PETCO2) and oxyhaemoglobin saturation via pulse oximetry (SpO2) were measured at rest and during submaximal cycling at 250 W. A hill climb (HC) performance test was conducted at sea level and after 14 d at altitude (ALT14) using a road of similar length (5.5-6 km) and gradient (4.8-5.3%). Power output was measured using SRM cranks. Average HC power at ALT14 was normalised to sea level power (HC%). Multiple regression was used to identify significant predictors of performance at altitude.
Results: At ALT15, there was a significant increase in resting VE (10.3 ± 1.9 vs. 12.2 ± 2.4 L·min(-1)) and HVR (0.34 ± 0.24 vs. 0.71 ± 0.49 L·min(-1)·%(-1)), while PETCO2 (38.4 ± 2.3 vs. 32.1 ± 3.3 mmHg) and SpO2 (97.9 ± 0.7 vs. 94.0 ± 1.7%) were reduced (P < .05). Multiple regression revealed ΔHVR and exercise VE at altitude as significant predictors of HC% (adjusted r(2) = 0.913; P = 0.003).
Conclusions: Ventilatory acclimatisation occurred during a 2 wk altitude training camp in elite cyclists and a higher HVR was associated with better performance at altitude, relative to sea level. These results suggest that ventilatory acclimatisation is beneficial for cycling performance at altitude.
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http://dx.doi.org/10.1080/17461391.2016.1139190 | DOI Listing |
Sci Rep
December 2024
Earth Observatory of Singapore, Nanyang Technological University, Singapore, 639798, Singapore.
Coastal populations are susceptible to relative sea-level (RSL) rise and accurate local projections are necessary for coastal adaptation. Local RSL rise may deviate from global mean sea-level rise because of processes such as geoid change, glacial isostatic adjustment (GIA), and vertical land motion (VLM). Amongst all factors, the VLM is often inadequately estimated.
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December 2024
Department of Geology, R R Lalan College, Bhuj, India.
The Great Rann of Kachchh is a sabkha terrain with a thick succession of Quaternary to Late Holocene sediments, deposited during high sea level after the Last Glacial Maxima. Geomorphologically, the Great Rann of Kachchh is subdivided into Bet Zone, Linear Trench Zone, Great Barren Zone, and Banni Plain. The Bet zone is a slightly elevated flat surface comprising a complex network of bets and interbet channels-the geomorphic entities developed as complex interplay of sea level and coseismic tectonic activity during the Holocene.
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December 2024
Department of Earth and Planetary Sciences, University of California, Riverside, CA, 92521, USA.
The Salton Sea (SS), California's largest inland lake at 816 square kilometers, formed in 1905 from a levee breach in an area historically characterized by natural wet-dry cycles as Lake Cahuilla. Despite more than a century of untreated agricultural drainage inputs, there has not been a systematic assessment of nutrient loading, cycling, and associated ecological impacts at this iconic waterbody. The lake is now experiencing unprecedented degradation, particularly following the 2003 Quantification Settlement Agreement-the largest agricultural-to-urban water transfer in the United States.
View Article and Find Full Text PDFBMC Complement Med Ther
December 2024
Division of internal Medicine, Institute of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Introduction: Sarcopenia is a disease primarily characterized by age-related loss of skeletal muscle mass, muscle strength, and/or decline in physical performance. Sarcopenia has an insidious onset which can cause functional impairment in the body and increase the risk of falls and disability in the elderly. It significantly increases the likelihood of fractures and mortality, severely impairing the quality of life and health of the elderly people.
View Article and Find Full Text PDFFish Shellfish Immunol
December 2024
Department of Biotechnology, School of Biological Engineering, Dalian Polytechnic University, Dalian 116034, Liaoning Province, P. R. China; Dalian Jinshiwan Laboratory, Dalian, China. Electronic address:
A number of studies have been demonstrated that arachidonate 5-lipoxygenase (ALOX-5) plays a role in regulating a range of physiological and pathological processes through the catalysis of leukotriene formation from arachidonic acid (ARA). The coding sequence of ALOX-5 from Apostichopus japonicus (Aj-ALOX-5) was successfully amplified, resulting in a 2028 bp ORF sequence that encodes 674 amino acids. A comparison of the amino acid sequence with those of other 5-lipoxygenases revealed that Aj-ALOX-5 has the N-terminal "PLAT domain" and C-terminal "lipoxygenase structural domain" characteristic of this enzyme family.
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