AI Article Synopsis

  • Streptococcus agalactiae is a significant pathogen, especially in pregnant women and newborns, but it's becoming more common in non-pregnant adults with chronic illnesses or weakened immune systems.* -
  • A case study highlights a middle-aged man with pre-existing health issues who showed severe symptoms of meningeal infection and unfortunately died within 24 hours of hospital admission.* -
  • The autopsy revealed multiple health problems linked to the bacteria, emphasizing the need for healthcare providers to consider S. agalactiae in serious invasive infections, even in atypical cases.*

Article Abstract

Streptococcus agalactiae is a well-known pathogen during pregnancy and in neonates. Among non-pregnant adults, invasive infection, although rare, is showing increasing frequency, especially in chronically ill, immunosuppressed, or older patients. Although rare, the clinical features of meningeal infection caused by S. agalactiae are similar to other bacterial meningitis. The authors report the case of a middle-aged man previously diagnosed with hypertension, diabetes mellitus, and alcoholic liver cirrhosis, who was admitted at the emergency department with a Glasgow Coma Scale of 11/12, generalized spasticity, bilateral Babinski sign, and hypertension. The clinical outcome was bad, with refractory shock and death within 24 hours of hospitalization. The bacteriological work-up isolated S. agalactiae in the cerebral spinal fluid (CSF), blood, and urine. An autopsy revealed meningoencephalitis, acute myocardial infarction, and pyelonephritis due to septic emboli. The authors point out the atypical CSF findings, the rapid fatal outcome, and the importance of including this pathogen among the etiologic possibilities of invasive infections in this group of patients.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757918PMC
http://dx.doi.org/10.4322/acr.2015.028DOI Listing

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