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Objective: To determine whether abdominal binders effectively control pain and distress after cesarean delivery.
Methods: A prospective randomized controlled trial was conducted between April and November, 2014, among women undergoing cesarean delivery (low-transverse skin incision) at two US hospitals. Participants were randomly allocated to either the abdominal binder or control groups on entry to the operating suite. Masking was not possible. Patients in the abdominal binder group were fitted with a device before leaving the operating room and were encouraged to wear it constantly, although breaks were allowed. The primary outcomes were postoperative distress (measured by the Symptom Distress Scale [SDS]) and pain (measured by a visual analog scale [VAS]). Individuals who asked to be removed from the study within 6hours of surgery were excluded from analyses.
Results: Analyses included 87 patients in the abdominal binder group and 68 in the control group. The abdominal binder and control groups did not differ in postoperative day 1 VAS (3.1±2.1 vs 3.4±2.3; P=0.33), postoperative day 2 VAS (3.0±1.9 vs 3.8±2.2; P=0.16), postoperative day 1 SDS (21.5±5.4 vs 21.8±5.1; P=0.87), and postoperative day 2 SDS (19.4±4.8 vs 19.9±5.0; P=0.53).
Conclusion: Postoperative pain and distress scores after cesarean delivery were not affected by abdominal binders. ClinicalTrials.gov:NCT02129894.
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http://dx.doi.org/10.1016/j.ijgo.2015.08.026 | DOI Listing |
Talanta
November 2024
Division of Abdominal Tumor Multimodality Treatment, Cancer Center, NHC Key Lab of Transplant Engineering and Immunology, Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, 610041, China; Sichuan Provincial Engineering Laboratory of Pathology in Clinical Application, West China Hospital, Sichuan University, Chengdu, 610041, China; Institutes for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address:
Although non-immunoglobin scaffold binders with high affinity and broad spectrum for albumin are attractive for lab-scale albumin purification, affinity chromatography based on these binders has not been developed. Here, the albumin-binding capabilities of representative binders, including protein G-derived albumin binding domain (ABD), albumin binding nanofitins (ABNF), and human serum albumin affimer 31 (HSA31) were predicted by interaction structure analysis and verified by experimental assays. Interaction structure prediction suggested that ABD possessed great potential to bind human (HSA), rhesus monkey (RhSA), mouse (MSA), and rat serum albumin (RSA), whereas ABNF might only bind HSA and bovine serum albumin (BSA), and HSA31 might not bind any of the tested albumins.
View Article and Find Full Text PDFHernia
November 2024
Department of Surgery, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Introduction: Abdominal binders consist of a wide compression belt that encircles the abdomen, theoretically supporting the abdominal wall. However, their use after ventral hernia repair is debated. Therefore, this meta-analysis evaluates their efficacy.
View Article and Find Full Text PDFJ Abdom Wall Surg
October 2024
Department of Digestive, Oncological, Endocrine, Hepato-Biliary, Pancreatic Surgery and Liver Transplantation, Trousseau Hospital, Tours University Hospital, Chambray-Lès-Tours, France.
Clin Pract
August 2024
The Ferrara Center for Patient Safety and Clinical Simulation, College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, NY 11568, USA.
The study focuses on the design and evaluation of inflatable abdominal binders for managing Orthostatic Hypotension. Orthostatic hypotension is a condition characterized by a significant drop in blood pressure when a person stands up, leading to symptoms such as dizziness, lightheadedness, and even fainting. The management of orthostatic hypotension typically involves a combination of pharmacological and non-pharmacological strategies.
View Article and Find Full Text PDFClin Auton Res
December 2024
Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, 506 Robinson Research Building, Nashville, TN, 37232-8802, USA.
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