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Purpose: To compare vestibulo-ocular reflex (VOR) gain values, gain symmetry between the semicircular canals (SCCs), and saccadic parameters in patients with a nosological diagnosis of Ménière's disease (MD) and vestibular migraine (VM).

Methods: Observational, descriptive, cross-sectional, retrospective study, approved by the Research Ethics Committee, under evaluation report number 4.462.

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Background: The pathological hallmark of Ménière's disease is endolymphatic hydrops, which can lead to an increase in basilar membrane stiffness and, consequently, an acceleration of the traveling wave of sound. The cochlear hydrops analysis masking procedure (CHAMP), which is an auditory brainstem response test masked at various frequencies with high-pass noise masking, uses the principle of the traveling wave velocity theory to determine the presence of endolymphatic hydrops.

Purpose: This study aimed to review the previous results of the CHAMP, expound the principles and key indicators, and discuss its clinical significance in diagnosing Ménière's disease.

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Article Synopsis
  • Triple semicircular canal plugging (TSCP) effectively alleviates vertigo in Meniere's disease (MD) patients, showing a 99% success rate in controlling symptoms.
  • The procedure carries a risk of hearing loss, with a reported rate of 22% among patients, which varies based on the duration of the disease and follow-up time.
  • TSCP is recommended as a surgical option for managing vertigo while preserving hearing in advanced MD patients.
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Article Synopsis
  • Endolymphatic hydrops, an increase in fluid within the cochlea, is a key feature of Meniere's disease, which causes symptoms like vertigo, fluctuating hearing loss, and tinnitus.
  • The study explored the relationship between endolymphatic hydrops and cochlear synaptopathy (a type of hearing loss) using imaging techniques on transgenic mice subjected to blast noise and osmotic changes.
  • Findings indicated that while both conditions can occur after noise exposure, endolymphatic hydrops does not cause cochlear synaptopathy; instead, they are independent effects resulting from damage to hair cell structures.
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: This study reviews the current literature on ocular movements, specifically focusing on nystagmus associated with peripheral vestibular disorders, to enhance diagnostic accuracy. The evaluation of ocular movements, particularly nystagmus, provides essential insights into the function and dysfunction of the vestibular system, helping clinicians distinguish between peripheral and central causes of vertigo and imbalance. : A comprehensive search of PubMed was conducted using key terms such as "ocular movements", "nystagmus", "vestibular nystagmus", and "peripheral vestibular disorders".

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