Water-soluble poly(2,7-dibenzosilole) as an ultra-bright fluorescent label for antibody-based flow cytometry.

Chem Commun (Camb)

Biosciences Division, Thermo Fisher Scientific Inc. 29851 Willow Creek Rd., Eugene, OR 97402, USA.

Published: March 2016

A series of novel water-soluble PEGylated dibenzosilole-based conjugated polymers were prepared as ultra-bright fluorescent labels for biomolecules. Due to their superior solubility and brightness, antibody conjugates labeled with functionalized polymers showed significantly enhanced signal and sensitivity relative to traditional fluorophores in functional flow cytometry applications.

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Source
http://dx.doi.org/10.1039/c5cc10347aDOI Listing

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