Objective: To report the clinical characteristics, neuto-imaging and prognosis of cavernous hemangioma of the optic chiasm.
Methods: Retrospective data analysis was conducted in 8 patients from Beijing Tongren Hospital and Beijing Tiantan Hospital. Patients' clinical characteristics, neuroimaging and prognosis were assessed.
Results: There were eight patients aging from 16-58 years old including 3 females and 5 males. The median age was 39.5 years. From the time of onset to diagnosis, the shortest time was 25 days and the longest was 2 years and 4 months. Clinical characteristics of 8 cases were analyzed. Among 8 cases, 3 patients had acute course, 3 patient had chronic course with acute exacerbation and 2 patients had chronic course. All patients presented with decreased visual acuity and/or visual field defect and 3 cases had headache. The most common initial manifestation was decreased visual acuity and/or visual field defect (4 cases). Only 4 cases were diagnosed cavernous hemangioma of the optic chiasm before surgery. The hemangioma was total resected in 6 patients and other two got partly removed. Visual function was improved in 4 cases after surgery. MRI showed mixed signal.
Conclusions: All patients presented decreased visual acuity and/or visual field defect, often accompanied with headache. It can be misdiagnosed at early stage. MRI may be helpful to the diagnosis. Complete resection at early stage may improve the visual function.
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Indian J Otolaryngol Head Neck Surg
January 2025
Department of ENT, Shaikh Zayed Hospital, Shaikh Zayed Medical Complex, Lahore, Pakistan.
Unlabelled: Cavernous hemangiomas are venous malformations characterized by interconnected channels of abnormally dilated blood vessels having low flow of blood. Whilst venous malformations most commonly affect the head and neck region, isolated cavernous hemangiomas of the palatine tonsils are extremely rare; with only 4 cases being reported in the English Literature. We report a case of a 43-year-old female who was referred to us for the evaluation and management of a right tonsillar swelling.
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Department of Ophthalmology, University of Paris Cité, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
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February 2025
Department of Surgery, University of Baghdad, College of Medicine, Baghdad, Iraq.
Background: With its vital ocular and adnexal structures, the orbit may be affected by a wide array of neoplasms, including primary, secondary, and metastatic neoplasms. These lesions pose significant diagnostic and therapeutic challenges in view of complex orbital anatomy and overlapping clinical presentations. This study aimed to analyze the epidemiology, clinical features, refractive impacts, and management outcomes of orbital tumors, providing insights to optimize diagnosis and treatment strategies.
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February 2025
Department of Medicine, University of California, San Diego, San Diego, United States.
Previously, we showed that propranolol reduces experimental murine cerebral cavernous malformations (CCMs) and prevents embryonic caudal venous plexus (CVP) lesions in zebrafish that follow mosaic inactivation of (Li et al., 2021). Because morpholino silencing of the β1 adrenergic receptor () prevents the embryonic CVP lesion, we proposed that plays a role in CCM pathogenesis.
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