Explicit solutions are presented in the Laplace and time domains for a one-variable Fokker-Planck equation governing the probability density of a random walker moving in a confining potential. Illustrative applications are discussed in two unrelated physical contexts: quantum yields in a doped molecular crystal or photosynthetic system, and the motion of signal receptor clusters on the surface of a cell encountered in a problem in immunology. An interesting counterintuitive effect concerning the consequences of confinement is found in the former, and some insights into the driving force for microcluster centralization are gathered in the latter application.
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http://dx.doi.org/10.1021/acs.jpcb.5b12548 | DOI Listing |
J Neurooncol
January 2025
Department of Neurosurgery, MacKay Memorial Hospital, No. 92, Sec. 2, Zhongshan N. Rd, Taipei, 10449, Taiwan.
Purpose: Advances in multidisciplinary treatment of childhood brain tumors have significantly prolonged survival and reduced treatment-related complications. This makes the accessibility of digital neurocognitive assessment an important issue in the post-pandemic era.
Methods: Twenty pediatric brain tumor patients were recruited between August 2023 and August 2024, and a total of eight standardized Cambridge Neuropsychological Test Automated Battery (CANTAB) tests targeting executive function, memory, and attention were applied on a digital system.
Chemistry
January 2025
Institute of Physical Chemistry Polish Academy of Sciences: Polska Akademia Nauk Instytut Chemii Fizycznej, Department IX Photochemistry and Spectroscopy, Kasprzaka 44/52, 01-224, Warsaw, POLAND.
We report on the U-shaped folding of flexible guest molecules of medicinal interest upon their inclusion into macrocyclic cavity of p-sulfonato-calix[4]arene in aqueous media. Alexidine and pentamidine are FDA-approved drug compounds currently rediscovered as potent membrane-targeting antibiotic adjuvants helping restore antibiotic activity against multidrug resistant bacteria pathogens. We have adopted host-guest and crystal engineering approach to study these drugs with a view of potential supramolecular formulations and/or crystal forms.
View Article and Find Full Text PDFLab Chip
January 2025
Department of Civil Engineering and Computer Science, University of Rome Tor Vergata, Rome, Italy.
Microfluidic impedance cytometry (MIC) is a label-free technique that characterizes individual flowing particles/cells based on their interaction with a multifrequency electric field. The technique has been successfully applied in different scenarios including life-science research, diagnostics, and environmental monitoring. The aim of this review is to illustrate the fascinating opportunities enabled by the integration of MIC with other microfluidic tools.
View Article and Find Full Text PDFCureus
December 2024
Department of Obstetrics and Gynaecology, Tata Main Hospital, Jamshedpur, IND.
An uncommon and recently identified Müllerian anomaly is the accessory cavitated uterine mass (ACUM). It is distinguished by the presence of a noncommunicating auxiliary cavity inside the uterus, located near and surrounded by uterine smooth muscle, and bordered by functioning endometrium beneath the round ligament's insertion, with a perfectly healthy uterus, ovaries, tubes, and cavity. Given that it is a congenital ailment with a persistent Müllerian duct at the level of the round ligament, primarily resulting from gubernaculum dysfunction, it usually manifests clinically as childhood dysmenorrhea in girls.
View Article and Find Full Text PDFPan Afr Med J
January 2025
Korea Foundation for International Healthcare, Tanzania Office, Dar es Salaam, Tanzania.
While the significance of strengthening the biomedical workforce in resource-limited settings has been widely acknowledged, there remains a paucity of information specific to the local context. In this regard, we underscore the importance of formulating a biomedical engineering policy based on empirical evidence. To provide such evidence, we conducted an analysis of the government-led biomedical training program in Tanzania, titled 'Capacity Enhancement of Medical Equipment Technical Services (CEOMETS)'.
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