Management of Multiple Myeloma Complicated by Hepatitis C Virus Reactivation: The Role of New Antiviral Therapy.

Open Forum Infect Dis

Departments of Infectious Diseases, Infection Control, and Employee Health.

Published: January 2016

Reactivation of chronic hepatitis C virus (HCV) infection has been reported in cancer patients receiving chemotherapy. In this study, we report the first case, to our knowledge, of thalidomide-induced acute exacerbation and reactivation of chronic HCV infection complicating management of multiple myeloma. Sofosbuvir-based antiviral therapy helped achieve viral clearance and normalization of liver enzymes, thus allowing access to future potentially life-saving chemotherapy agents.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751339PMC
http://dx.doi.org/10.1093/ofid/ofv211DOI Listing

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