An unusual case of eyelid metastasis from a rectal primary.

A 26-year-old, human immunodeficiency virus. (HIV).negative male, a diagnosed case of locally advanced adenocarcinoma rectum underwent diversion colostomy and received preoperative radiotherapy with three-dimensional conformal radiotherapy. (3DCRT) to a dose of 25 Gy/5 Fx/8. days to 95% planning target volume. (PTV) with 3-field technique. (right and left lateral and posterior) by 6 and 15 MV photons. Postradiotherapy contrast-enhanced computed tomography. (CECT) chest and abdomen showed progressive disease. He was reviewed by oncosurgeon and considered inoperable. He presented with a swelling over upper eyelid, which on biopsy was proven as metastatic adenocarcinoma. He received three cycles of weekly chemotherapy and was planned for excision and reconstruction of eyelid. He finally succumbed due to small bowel obstruction, acute renal failure, and septicemia after an overall duration of survival of seven months. Eyelid metastases occur in less than one percent of malignant eye lesions in adults. To the best of our knowledge, this is the first case reported with a primary in rectum.