AI Article Synopsis
- The study investigates the risks and benefits of neck dissection in patients with low-risk differentiated thyroid cancer (DTC) without detectable lymph nodes.
- It compares two groups: one that underwent neck dissection (C+) and one that did not (C-), analyzing outcomes like remission rates, disease progression, and complications.
- Results indicate no significant difference in remission or progression rates between the two groups, but the C+ group experienced a higher rate of permanent complications, suggesting that neck dissection may not be beneficial for low-risk DTC patients.
Article Abstract
Background: The benefit of neck dissection is the subject of debate in differentiated thyroid cancer (DTC). We analyze the risk-benefit of neck dissection for low-risk DTC without detectable lymph nodes.
Methods: We conducted a retrospective study from 1983 to 2003; which included 295 patients without detectable lymph nodes who were treated by thyroidectomy with (C+) or without (C-) neck dissection. All patients had iodine131 therapy. We compared the frequency of remission, disease progression, and permanent complications between groups.
Results: Two hundred twelve patients comprised the C+ group, and 83 patients the C- group. Respectively for C+ versus C-, remission rates were 92% versus 89.2% (p = .40), and progressive disease observed was 3.3% versus 7.2% (p = .10). Permanent hypoparathyroidism occurred in 15.1% in C+ versus 3.6% in C- (p = .006).
Conclusion: The risk-benefit analysis of neck dissection in patients with low-risk DTC shows no benefit in terms of complete remission or occurrence of progression. However, risk of complications seems to be higher in patients with neck dissection. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1091-1096, 2016.
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| http://dx.doi.org/10.1002/hed.24402 | DOI Listing |
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