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Tramadol as a fentanyl adulterant: Prevalence and management in a ToxIC Fentalog study prospective cohort.
Am J Emerg Med
December 2024
Icahn School of Medicine at Mount Sinai, Center for Research on Emerging Substances, Poisoning, Overdose, and New Discoveries (RESPOND), NYC Health + Hospitals/Elmhurst, New York, NY, USA.
Background: Tramadol is an adulterant of illicit opioids. As it is a serotonin-norepinephrine reuptake inhibitor as well as a μ-opioid agonist, tramadol adulteration may worsen overdose signs and symptoms or affect the amount of naloxone patients receive.
Methods: This is a multicenter, prospective cohort of adult patients with suspected opioid overdoses who presented to one of eight United States emergency departments and were included in the Toxicology Investigators Consortium's Fentalog Study.
Analysis of hair styling wax residues on human hair: A forensic investigation with ATR-FTIR spectroscopy and chemometric interpretation.
Forensic Sci Int
January 2025
Department of Forensic Science, Punjabi University, Patiala, Punjab 147002, India. Electronic address:
A comparative analysis of hair evidence recovered from the crime scene and the hair of suspects or victims is common in the forensic scenario. However, its evidentiary value increases with cosmetic applications like gel, wax, spray, or other hair treatments. Therefore, after extracting these products from hair strands, they can link the victim and accused to the crime scene and with each other, serving as corroborative evidence.
View Article and Find Full Text PDFPrevalence and predictors of HIV among patients presenting to US emergency departments with opioid overdose.
Drug Alcohol Depend
November 2024
Mount Sinai Center for Research on Emerging Substances, Poisoning, Overdose, and New Discoveries (RESPOND), Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, NYC Health + Hospitals/Elmhurst, New York, NY, United States.
Article Synopsis
- Opioid overdose deaths in the U.S. have dramatically increased due to the rise of illicit fentanyl, which also raises the risk of HIV infection among those affected by injection drug use.
- A study analyzed data from 1,690 patients who experienced acute opioid overdoses across 10 hospitals to identify HIV prevalence and associated risk factors.
- The findings revealed that 5.6% of patients with known HIV status were HIV positive, with stimulant use being more common among HIV-positive individuals and a significant link found between bipolar psychiatric history and increased HIV risk.
Bitemark analysis comparing the use of digital scans and 3D resin casts.
J Forensic Odontostomatol
August 2024
Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Although dental patterns are unique, the use of bitemark analysis in personal identification remains controversial. To accurately reproduce and compare three-dimensional models of bitemarks and dental arches, intraoral three-dimensional scans, commonly utilized in clinical dental practice for precise and stable digital impressions, are recommended. This study aims to compare two different techniques for bitemark analysis: a digital method based on the superimposition of digital scans of dental patterns and lesions, and a visual method based on the physical superimposition of impressions and resin casts produced by 3D printing.
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