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Antimicrobial susceptibility and epidemiological types of Legionella pneumophila human isolates from Italy (1987-2020).
J Glob Antimicrob Resist
January 2025
Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy; ESCMID Study Group for Legionella Infections (ESGLI), Basel, Switzerland. Electronic address:
Background: Although antimicrobial resistance has not yet emerged as an overarching problem for Legionella pneumophila (Lp) infection, the description of clinical and environmental strains resistant to fluoroquinolones and macrolides is a cause of concern. This study aimed to investigate the antimicrobial susceptibility of Lp human isolates in Italy.
Methods: A total of 204 Lp clinical isolates were tested for sensitivity to nine antibiotics using the broth microdilution assay (BMD).
Hippocampal Sclerosis After Legionnaires' Disease: A Case Report.
Cureus
December 2024
Department of Psychiatry, University of Occupational and Environmental Health, Japan, Kitakyushu, JPN.
Legionnaires' disease is a form of atypical pneumonia that can present with neurological symptoms, such as headaches, seizures, and focal neurological abnormalities. We report the case of a male patient who developed impaired consciousness and recurrent seizures following pneumonia caused by . The patient received antibiotics and antiepileptic treatment and was discharged on hospital day 56.
View Article and Find Full Text PDFRapid Icm/Dot T4SS Inactivation Prevents Resuscitation of Heat-Induced VBNC Legionella pneumophila by Amoebae.
Environ Microbiol
January 2025
Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland.
Legionella pneumophila, the causative agent of Legionnaires' disease, employs the Icm/Dot Type IV secretion system (T4SS) to replicate in amoebae and macrophages. The opportunistic pathogen responds to stress by forming 'viable but non-culturable' (VBNC) cells, which cannot be detected by standard cultivation-based techniques. In this study, we document that L.
View Article and Find Full Text PDFScoping review of infectious disease prevention, mitigation and management in passenger ships and at ports: mapping the literature to develop comprehensive and effective public health measures.
Trop Med Health
January 2025
Laboratory of Hygiene and Epidemiology, Faculty of Medicine, University of Thessaly, 22 Papakyriazi Street, 41222, Larissa, Thessaly, Greece.
Background: With various infectious disease risks to passenger ship travellers, guidance for infectious disease prevention, mitigation and management (PMM) exists. Emerging infections and emergencies necessitate updated, context-specific guidelines and practices. New evidence for infection PMM must be translated into guidance for governmental authorities and the passenger ship industry.
View Article and Find Full Text PDFSpontaneous pulmonary-twist secondary to Legionnaire's disease.
Intensive Care Med
January 2025
Department of Medical Intensive Care, University Hospital of Strasbourg, Nouvel Hôpital Civil, Strasbourg, France.
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