Aim: Describe patients,' providers' and healthcare system leaders' perceptions of pharmacogenetic research to guide tobacco cessation treatment in an American Indian/Alaska Native primary care setting.
Materials & Methods: This qualitative study used semistructured interviews with 20 American Indian/Alaska Native current or former tobacco users, 12 healthcare providers and nine healthcare system leaders.
Results: Participants supported pharmacogenetic research to guide tobacco cessation treatment provided that a community-based participatory research approach be employed, research closely coordinate with existing tobacco cessation services and access to pharmacogenetic test results be restricted to providers involved in tobacco cessation.
Conclusion: Despite a history of mistrust toward genetic research in tribal communities, participants expressed willingness to support pharmacogenetic research to guide tobacco cessation treatment.
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http://dx.doi.org/10.2217/pgs.15.177 | DOI Listing |
Cochrane Database Syst Rev
January 2025
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Background: People from lower socioeconomic groups are more likely to smoke and less likely to succeed in achieving abstinence, making tobacco smoking a leading driver of health inequalities. Contextual factors affecting subpopulations may moderate the efficacy of individual-level smoking cessation interventions. It is not known whether any intervention performs differently across socioeconomically-diverse populations and contexts.
View Article and Find Full Text PDFTob Prev Cessat
January 2025
Institute for Mental Health and Policy Research, Centre for Addiction and Mental Health, Toronto, Canada.
Introduction: Rural regions generally report higher smoking rates than urban centers, which increases the risk of tobacco related harms and consequences, and makes promoting smoking cessation in these areas a priority. Mass distribution of nicotine replacement therapy (NRT) by postal mail has been found to increase the odds of successful cessation attempts. Understanding factors that contribute to the use of NRT could help maximize this intervention's effectiveness.
View Article and Find Full Text PDFAJPM Focus
February 2025
Department of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, Florida.
Introduction: The growing prevalence of E-cigarette use among adolescents is alarming because it increases the probability of persistent tobacco use and addiction to nicotine. Healthcare providers are in a unique position to influence their patients' use of E-cigarettes. The purpose of the study is to determine the frequency at which providers screen adolescents for E-cigarette use and advise against use during healthcare visits.
View Article and Find Full Text PDFAJPM Focus
February 2025
Center for Healthcare Policy Research, University of California, Davis, Sacramento, California.
Introduction: People who are covered by Medicaid have a higher smoking prevalence than the general population and are at an increased risk for tobacco-related disease, a major driver of Medicaid costs. California has the largest Medicaid program, called Medi-Cal, whose members also have higher tobacco-use rates and tobacco-related disease. Quitting is beneficial at any age, and health professional advice and assistance are a key indicator of smoking cessation.
View Article and Find Full Text PDFJ Clin Med
January 2025
Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium.
Substance use during pregnancy is associated with adverse outcomes for both mother and child. This study aimed to determine the prevalence and determinants of alcohol, tobacco and illicit drug use before and during pregnancy in Belgium. An observational study was conducted using data from the longitudinal BELpREG registry.
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