The importance of matrix-assisted laser desorption ionization-time of flight mass spectrometry for correct identification of Clostridium difficile isolated from chromID C. difficile chromogenic agar.

Jonathan H K Chen Vincent C C Cheng Oi-Ying Wong Sally C Y Wong Simon Y C So Wing-Cheong Yam Kwok-Yung Yuen

J Microbiol Immunol Infect

Department of Microbiology, Queen Mary Hospital, Hong Kong Special Administrative Region, China; Carol Yu Centre for Infection, University of Hong Kong, Hong Kong Special Administrative Region, China. Electronic address:

Published: October 2017

The clinical workflow of using chromogenic agar and matrix-assisted laser desorption ionization time-of-fight mass spectrometry (MALDI-TOF MS) for Clostridium difficile identification was evaluated. The addition of MALDI-TOF MS identification after the chromID C. difficile chromogenic agar culture could significantly improve the diagnostic accuracy of C. difficile.

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http://dx.doi.org/10.1016/j.jmii.2015.12.002	DOI Listing

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