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Article Synopsis
  • A 3-year-old male standard poodle mix was presented with severe health issues including vomiting, difficulty breathing, and lethargy, which led to a diagnosis of a peritoneal pericardial diaphragmatic hernia (PPDH) involving the liver and gallbladder.
  • Emergency surgery revealed serious complications including a necrosed liver lobe, gallbladder issues, and suspected right ventricular aneurysms, which were treated during the operation.
  • Post-surgery, the dog experienced ventricular arrhythmia but was successfully managed and discharged after 4 days, showing good recovery after 12 months; this case highlights the rarity and risks associated with right ventricular aneurysms in dogs.
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A sustained calcium response mediated by IP3 receptor anchoring to the desmosome is essential for apoptotic cell elimination.

Curr Biol

October 2024

Department of Biology, Faculty of Sciences, Kyushu University, Fukuoka 819-0395, Japan; Department of Biochemistry, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan. Electronic address:

Efficient elimination of apoptotic cells within epithelial cell sheets is crucial for preserving epithelial barrier integrity. It is well established that immediate neighbors of an apoptotic cell actively participate in its removal by enclosing it within a wall of actomyosin, pushing it out in a purse-string manner in a process called apical extrusion. Here, we found that sustained elevation of calcium ions in neighboring epithelial cells is necessary to generate the contractility required for apoptotic cell elimination.

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Article Synopsis
  • Upper limb (UL) amputation is a significant disability affecting daily life, with many patients dissatisfied with existing prosthetic options due to issues like lack of sensation and comfort.
  • Transcutaneous osseointegration (PFOI) offers a promising solution by surgically implanting a device that allows direct bone anchoring, improving prosthetic control and wear time without the bulk of a traditional socket.
  • The article outlines a surgical method for PFOI after forearm amputation, emphasizing careful technique to protect nerves and vessels, and highlights the importance of a motivated patient and engaged prosthetist for successful rehabilitation.
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Revision Amputation with Press-Fit Osseointegration for Transfemoral Amputees.

JBJS Essent Surg Tech

June 2022

Limb Lengthening and Complex Reconstruction Service, Osseointegration Limb Replacement Center, Hospital for Special Surgery, New York, NY.

Unlabelled: Press-fit transfemoral osseointegration is the technique of inserting an intramedullary metal implant into the residual femur of an amputee; the implant is passed transcutaneously to attach to a standard prosthesis that includes a knee, tibia, ankle, and foot. This allows the prosthesis to be skeletally anchored, eliminating socket-related problems such as tissue compression that can provoke neurogenic pain, skin abrasion, and fitting problems resulting from residual limb size fluctuation. Amputees with osseointegrated prostheses typically wear their prosthesis more and experience better mobility, quality of life, and extremity proprioception compared to those with socket prostheses.

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Purpose: The "Purse-String Technique" (PST) is an arthroscopic horizontal mattress suture technique for recurrent anterior shoulder instability that uses a single double-loaded suture anchor at the 4-o' clock position, achieving a Bankart labral repair and an infero-superior capsular shift. In this study, we describe the long-term results of the PST.

Methods: The study included 69 individuals (70 shoulders), with a mean age of 30 years, who had recurrent post-traumatic anteroinferior instability.

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