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http://dx.doi.org/10.1007/s11248-016-9931-y | DOI Listing |
Plants (Basel)
December 2024
Jiangsu Academy of Forestry, Nanjing 211153, China.
The paulownia tree belongs to the Paulowniaceae family. Paulownia has strong vitality; has strong adaptability to harsh environmental conditions; and can be used as building raw material, as well as processing drugs and having other purposes. In the research field of MYB transcription factors of the paulownia tree, it is rare to discuss the resistance to abiotic stress.
View Article and Find Full Text PDFBMC Plant Biol
January 2025
Laboratory of Plant Chemical Biology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto, 606-8502, Japan.
Background: Mongolian grasslands, including the Gobi Desert, have been exposed to drought conditions with few rains. In such harsh environments, plants with highly resistant abilities against drought stress survive over long periods. We hypothesized that these plants could harbor novel and valuable genes for enhancing drought stress resistance.
View Article and Find Full Text PDFBackground: Belzutifan, a first-in-class HIF-2α inhibitor, has shown antitumour activity as monotherapy and in combination with cabozantinib in patients with previously treated advanced kidney cancer. The phase 2 LITESPARK-003 study was designed to determine the antitumour activity and safety of belzutifan in combination with cabozantinib in patients with advanced clear-cell renal cell carcinoma that was previously untreated (cohort 1) or previously treated with immunotherapy (cohort 2). Here, we report results from cohort 1 of this clinical trial.
View Article and Find Full Text PDFPhytochemistry
December 2024
State Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, China. Electronic address:
Poplar tree growth is frequently hindered by environmental stressors, particularly soil salinization. Enhancing salt tolerance is essential for improving their adaptability and biomass under these conditions. The Stress-Associated Protein (SAP) family, characterized by A20/AN1 zinc finger domains, plays a crucial role in plants' tolerance to abiotic stress.
View Article and Find Full Text PDFExp Eye Res
December 2024
Department of Medical Genetics, University of British Columbia, Life Sciences Institute, 2350 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada. Electronic address:
The Mitf transcription factor is a critical regulator of the melanocyte lineage and eye development. Mitf activity in different cell types is controlled in part by ten alternative promoters and their resulting isoforms. A useful tool for melanocyte-based research, Mitf-cre was designed to express Cre from the Mitf-M promoter, which is melanocyte specific.
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