Study Objectives: To investigate how the effects of targeted memory reactivation (TMR) are influenced by memory accuracy prior to sleep and the presence or absence of direct cue-memory associations.
Methods: 30 participants associated each of 50 pictures with an unrelated word and then with a screen location in two separate tasks. During picture-location training, each picture was also presented with a semantically related sound. The sounds were therefore directly associated with the picture locations but indirectly associated with the words. During a subsequent nap, half of the sounds were replayed in slow wave sleep (SWS). The effect of TMR on memory for the picture locations (direct cue-memory associations) and picture-word pairs (indirect cue-memory associations) was then examined.
Results: TMR reduced overall memory decay for recall of picture locations. Further analyses revealed a benefit of TMR for picture locations recalled with a low degree of accuracy prior to sleep, but not those recalled with a high degree of accuracy. The benefit of TMR for low accuracy memories was predicted by time spent in SWS. There was no benefit of TMR for memory of the picture-word pairs, irrespective of memory accuracy prior to sleep.
Conclusions: TMR provides the greatest benefit to memories recalled with a low degree of accuracy prior to sleep. The memory benefits of TMR may also be contingent on direct cue-memory associations.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835313 | PMC |
| http://dx.doi.org/10.5665/sleep.5772 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Active Inference Model of Coherence Therapy.
Front Hum Neurosci
January 2023
Chamberlin Applied Neuroscience, Glastonbury, CT, United States.
Coherence Therapy is an empirically derived experiential psychotherapy based on Psychological Constructivism. Symptoms are viewed as necessary output from an implicit model of the world. The therapist curates experiences and directs attention toward discovering the model.
View Article and Find Full Text PDFPhosphoproteomic analysis of cocaine memory extinction and reconsolidation in the nucleus accumbens.
Psychopharmacology (Berl)
January 2019
Department of Psychiatry, Yale University, New Haven, CT, USA.
Rationale: Environmental stimuli, or cues, associated with the use of drugs such as cocaine are one of the primary drivers of relapse. Thus, identifying mechanisms to reduce the motivational properties of drug cues is an important research goal.
Objectives: The purpose of this study was to identify cellular signaling events in the nucleus accumbens (NAc) that are induced when a cocaine cue memory is either extinguished through repeated cue presentation in the absence of drug, or when the memory is reactivated and reconsolidated by a brief cue re-exposure.
Neural Correlates of Direct and Indirect Suppression of Autobiographical Memories.
Front Psychol
April 2016
School of Psychology and Neuroscience, University of St AndrewsSt Andrews, UK; School of Natural Sciences, University of StirlingStirling, UK.
Research indicates that there are two possible mechanisms by which particular target memories can be intentionally forgotten. Direct suppression, which involves the suppression of the unwanted memory directly, and is dependent on a fronto-hippocampal modulatory process, and, memory substitution, which includes directing one's attention to an alternative memory in order to prevent the unwanted memory from coming to mind, and involves engaging the caudal prefrontal cortex (cPFC) and the mid-ventrolateral prefrontal cortex (VLPFC) regions. Research to date, however, has investigated the neural basis of memory suppression of relatively simple information.
View Article and Find Full Text PDFThe Benefits of Targeted Memory Reactivation for Consolidation in Sleep are Contingent on Memory Accuracy and Direct Cue-Memory Associations.
Sleep
May 2016
Department of Psychology, University of York, United Kingdom.
Study Objectives: To investigate how the effects of targeted memory reactivation (TMR) are influenced by memory accuracy prior to sleep and the presence or absence of direct cue-memory associations.
Methods: 30 participants associated each of 50 pictures with an unrelated word and then with a screen location in two separate tasks. During picture-location training, each picture was also presented with a semantically related sound.
Examining the influence of a spatially irrelevant working memory load on attentional allocation.
J Exp Psychol Hum Percept Perform
August 2013
Department of Psychology, University of Nebraska–Lincoln, Lincoln, NE 68588, USA.
The present study examined the influence of holding task-relevant gaze cues in working memory during a target detection task. Gaze cues shift attention in gaze-consistent directions, even when they are irrelevant to a primary detection task. It is unclear, however, whether gaze cues need to be perceived online to elicit these effects, or how these effects may be moderated if the gaze cues are relevant to a secondary task.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!