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Significant Disparities in Adolescents With Severe Traumatic Brain Injury Across Trauma Center Types: Wide Variation of Tracheostomy and Gastrostomy.
Crit Care Med
January 2025
Department of Surgery, University of Southern California, Los Angeles, CA.
Objectives: To explore practice variations in the rate and timing of tracheostomy and gastrostomy for adolescent with severe traumatic brain injury (TBI) across trauma center types.
Design: Retrospective cohort study.
Setting: Trauma centers participating in the American College of Surgeons Trauma Quality Improvement Program (2017-2021) included adult (ATC), mixed (MTC), and pediatric trauma centers (PTC).
Spinal cord injury-specific prognostic risk assessment tool for development of type 2 diabetes.
J Spinal Cord Med
January 2025
Stanford-Surgery Policy Improvement Research & Education Center, Stanford School of Medicine, Stanford, CA, USA.
Context: Available diabetes risk calculators were developed for able-bodied individuals, but their metabolic profile is different from individuals with spinal cord injury.
Objectives: We aimed to develop a diabetes risk assessment tool specific to individuals with spinal cord injury.
Methods: We used national Veterans Affairs data to identify patients with at least a 2-year history of spinal cord injury and no prior history of diabetes with a Veterans Heath Affairs visit from 2005-2007, and followed the 11,054 individuals that met inclusion criteria for up to 17 years to assess diabetes development.
Iron-Quercetin complex enhances mesenchymal stem cell-mediated HGF secretion and c-Met activation to ameliorate acute kidney injury through the prevention of tubular cell apoptosis.
Regen Ther
March 2025
Research Center for Integrated Traditional Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, China.
Background: Acute kidney injury (AKI) is a life-threatening clinical syndrome with no effective treatment currently available. This study aims to investigate whether Iron-Quercetin complex (IronQ) pretreatment can enhance the therapeutic efficacy of Mesenchymal stem cells (MSCs) in AKI and explore the underlying mechanisms.
Methods: A cisplatin-induced AKI model was established in male C57BL/6 mice, followed by the intravenous administration of 1x10ˆ6 MSCs or IronQ-pretreated MSCs (MSC).
Detection and Identification in Reported Mushroom Poisoning Incidents - China, 2012-2023.
China CDC Wkly
December 2024
State Key Laboratory of Trauma, Burn and Combined Injury, Third Military Medical University, Chongqing, China.
What Is Already Known About This Topic?: Mushroom poisoning incidents are one of the major causes of death by foodborne outbreaks in China. Effective detection and identification can provide the foundation for determining the cause of the incidents and the early diagnosis and treatment of patients.
What Is Added By This Report?: The surveillance data from the Public Health Emergency Management Information System, China CDC, showed that incidents with laboratory test results as the basis for determining the cause of mushroom poisoning accounted for only 14.
Acute Effects of Unplanned and Planned Hop-Landing Training on Neurocognitive Function and Knee Biomechanics.
Orthop J Sports Med
January 2025
School of Sport, Rehabilitation, and Exercise Sciences, University of Essex, Wivenhoe Park, Colchester, Essex, United Kingdom.
Background: Athletes with decreased baseline neurocognitive function may experience noncontact anterior cruciate ligament (ACL) injury in unanticipated athletic situations. Many ACL injury prevention programs (IPPs) focus on improving closed-skill movements (eg, planned landing). However, the more open-skill movements (eg, unplanned reactive movements) required in unpredictable sports scenarios are commonly absent from ACL IPPs, and the acute effects of open-skill training on neurocognitive function remain unclear.
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