AI Article Synopsis
- The study investigated how dairy products "Bifidin" and "Prolacta," enriched with micronutrients, affect the antioxidant glutathione system in male rats under excessive exercise loads.
- Researchers found that excessive exercise induces oxidative stress, leading to decreased levels of reduced glutathione and lower activity of selenium-dependent glutathione-peroxidase in the rats.
- Regular consumption of the dairy products significantly helps counteract lipid peroxidation and restore glutathione system functioning, particularly increasing glutathione-S-transferase activity in liver tissue alongside "Bifidin" consumption.
Article Abstract
There was performed the study of the activity of the antioxidant system of glutathione under regular taking of enriched with micronutrients dairy products "Bifidin " and "Prolacta" in conditions ofsimulation of xcessive exercise loads. Target of research: white outbred male rats weighing 180-200 g (n = 68). Research methods and equipment: information retrieval, biochemical, and statistical. In the subacute experiment there was established that in conditions of excessive exercise loads (CEEL) the body of the rat meets with significant oxidative stress, causing the suppression of the activity of glutathione system: the number of reduced glutathione and the activity of selenium-dependent glutathione-peroxidase decline. Regular taking of dairy products "Bifidin" and "Prolacta" in conditions of CEEL (active training process) allows effectively to neutralize lipid peroxidation processes and normalize indices of the system of glutathione. There is established an increase in the activity ofglutathione-S-transferase in the homogenates of liver tissue in the simulation CEEL in combination with the use ofproduct "Bifidin".
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