AI Article Synopsis

  • The study explored anterior pituitary function in hypertensive patients before and after a 15-day captopril treatment, which inhibits Angiotensin II production.
  • No significant changes were found in pituitary hormones overall, except for a notable reduction in the response of ACTH to low blood sugar levels post-treatment.
  • The authors suggest Angiotensin II may play a role in influencing certain functions of the pituitary gland.

Article Abstract

The Authors investigated anterior pituitary function in hypertensive patients in basal conditions and following a 15-day course of treatment with captopril, a drug which blocks the generation of Angiotensin II (Angio II). No differences were observed for any of the pituitary hormones except ACTH, whose response to hypoglycemia was significantly blunted by the pharmacological treatment. A possible role of Angio. II in modulating some aspects of pituitary function is proposed.

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http://dx.doi.org/10.1007/BF03350017DOI Listing

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