Background: As evidence mounts regarding associations between genetics and body weight, it is essential to understand how to communicate this information, and factors like emotion that could moderate the effectiveness of messages.
Purpose: We assessed influences of emotion on reactions to weight-related genomic information in a virtual clinical setting.
Methods: An online representative US sample of overweight women was randomized to receive an emotion induction (anger, fear, or neutral) paired with information about genomic or behavioral influences on weight in an interaction with a virtual doctor.
Results: Receiving genomic information led to reduced attributions of lifestyle causes for weight and behavioral intentions, but only among individuals in a fear state.
Conclusions: The current study is among the first to reinforce the concern that discussing genomic underpinnings of overweight could undercut health behavior, and highlights the importance of identifying factors like emotion that influence interpretation of genomic information. Clinicaltrials.gov NCT01888913.
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http://dx.doi.org/10.1007/s12160-016-9771-2 | DOI Listing |
Psychopharmacology (Berl)
January 2025
Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Canada.
Rationale: Clinical literature indicates there may be a therapeutic use of cannabidiol (CBD) for stress-related disorders. Preclinical literature remains conflicted regarding the underlying neurobehavioral mechanisms, reporting mixed effects of CBD (increased, decreased, or no effect) on anxiety- and fear-related behaviors. Preclinical data demonstrated that CBD modulates hypothalamus-pituitary-adrenal (HPA) axis gene expression; it is unknown whether CBD changes HPA axis responsivity and how this relates to altered behavior.
View Article and Find Full Text PDFBMC Public Health
January 2025
Center for Global Health, Weill Cornell Medicine, 402 East 67 Street, 2 Floor, New York, NY, 10065, USA.
Background: Uncontrolled hypertension is the leading modifiable risk factor for cardiovascular disease mortality and remains high in low-middle income countries like Haiti. Barriers and facilitators to achieving hypertension control in urban Haiti remain poorly understood. Elucidating these factors could lead to development of successful interventions.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
January 2025
Department of Women's and Children's Health, Uppsala University, Uppsala, 751 85, Sweden.
Background: Stillbirth occurs at a rate of 3.0 per thousand in Sweden. However, few studies have focused on the initial experiences of parents facing a stillbirth.
View Article and Find Full Text PDFCogn Affect Behav Neurosci
January 2025
Departamento de Psicología ClínicaPsicobiología y MetodologíaFacultad de Psicología, Universidad de La Laguna, La Laguna, 38200, Tenerife, Spain.
Small animal phobia (SAP) is a subtype of specific phobia characterized by an intense and irrational fear of small animals, which has been underexplored in the neuroscientific literature. Previous studies often faced limitations, such as small sample sizes, focusing on only one neuroimaging modality, and reliance on univariate analyses, which produced inconsistent findings. This study was designed to overcome these issues by using for the first time advanced multivariate machine-learning techniques to identify the neural mechanisms underlying SAP.
View Article and Find Full Text PDFUrogynecology (Phila)
October 2024
Aava Medical Center, Hämeenlinna, Finland.
Importance: Although surgery for pelvic organ prolapse (POP) is generally associated with an improvement in sexual function, knowledge on specific changes is limited.
Objectives: The aim of this study was to describe and compare changes in sexual activity and function during a 5-year follow-up period after POP surgery.
Study Design: This was a nationwide cohort study of 3,515 women operated on for POP in 2015 in Finland.
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