Partial hand amputation is perhaps the most frequent amputation level, worldwide. Although its annual incidence in western countries is roughly 1:18 000 inhabitants, the treatments of partial hand amputations have modestly progressed so far. We have identified three main limitation factors to this progress: 1) the wide range of anatomical and functional presentations, which makes difficult to find standardized and scalable solutions; 2) the technological complexity in replacing the motor and sensory function of a lost digit in the size of a digit; and 3) the fact that a partial hand can be functionally successful mostly when it restores a lost opposition movement, i.e., the ability to oppose the thumb against the fingers while providing enough grasping force and aperture width. This review presents an overview of the existing surgical and technological solutions for treating partial hand amputations, and is specifically targeted to (biomedical) engineers. We critically highlighted the advantages, limitations, and open challenges. Remarkably, current fitting procedures rely on manual approaches by skilled prosthetic technicians rather than on modern engineering methods. Hence, the objective of this study is to comprehensively but concisely overview the field in order to inspire engineers to develop new systems and procedures able to address current open issues.
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http://dx.doi.org/10.1109/RBME.2016.2523799 | DOI Listing |
Immunooncol Technol
December 2024
Department of Biomedicine, University of Basel, Basel, Switzerland.
Background: Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TIL) is a personalized immunotherapy. The efficacy of TIL-ACT has been demonstrated prospectively in patients with advanced melanoma but is not limited to melanoma patients. Many patients are refractory to TIL-ACT, however, or their cancer becomes resistant.
View Article and Find Full Text PDFAsia Pac J Sports Med Arthrosc Rehabil Technol
January 2025
Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Background: Persistent maladaptive changes of corticospinal tract (CST) and quadriceps strength deficits exist in patients with anterior cruciate ligament reconstruction (ACLR). This study aimed to investigate the relationships between the structural alterations of CST and quadriceps muscle strength deficits in patients with ACLR.
Methods: Twenty-nine participants who had undergone unilateral ACLR (29 males; age = 32.
Ann Thorac Surg Short Rep
June 2024
Department of Thoracic Surgery, University Hospital Basel, Basel, Switzerland.
Background: Sternoclavicular joint infection is rare. Operation is the treatment of choice, but there is no generally accepted approach. This report evaluated the clinical and functional results after extended surgical treatment.
View Article and Find Full Text PDFJ Neuroeng Rehabil
January 2025
Department of Biomedical Engineering, Faculty of Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
Background: Motion complexity is necessary for adapting to external changes, but little is known about trunk motion complexity during seated perturbation in individuals with spinal cord injury (SCI). We aimed to investigate changes following SCI in trunk segmental motion complexity across different perturbation directions and how they affect postural control ability in individuals with SCI.
Methods: A total of 17 individuals with SCI and 18 healthy controls participated in challenging sagittal-seated perturbations with hand protection.
Hand Surg Rehabil
January 2025
AOU di Modena - SC Chirurgia della Mano, Italy.
Most patients with post-traumatic and/or degenerative wrist arthritis present with pain and limitation of activities of daily living. Wrist denervation using a two-incision technique is an alternative to proximal row carpectomy and partial or total wrist arthrodesis. The purpose of this study was to evaluate whether two-incision denervation is a valid procedure for reducing pain in wrist arthritis of different etiologies.
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