AI Article Synopsis
- The demand for scaffolds in bone tissue engineering (BTE) has led to a variety of polymers being used for effective scaffold fabrication.
- Chitosan (CS) has gained popularity as a graft material, either on its own or combined with other materials, due to its beneficial properties for BTE.
- Key properties needed for scaffolds in BTE include porosity, biocompatibility, mechanical strength, and biodegradability, and this review focuses on CS and its role alongside other materials in bone tissue repair.
Article Abstract
The clinical demand for scaffolds and the diversity of available polymers provide freedom in the fabrication of scaffolds to achieve successful progress in bone tissue engineering (BTE). Chitosan (CS) has drawn much of the attention in recent years for its use as graft material either as alone or in a combination with other materials in BTE. The scaffolds should possess a number of properties like porosity, biocompatibility, water retention, protein adsorption, mechanical strength, biomineralization and biodegradability suited for BTE applications. In this review, CS and its properties, and the role of CS along with other polymeric and ceramic materials as scaffolds for bone tissue repair applications are highlighted.
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| http://dx.doi.org/10.1016/j.ijbiomac.2016.01.112 | DOI Listing |
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