AI Article Synopsis
- Unblocked fleas can transmit Yersinia pestis, the plague-causing bacterium, shortly after getting an infectious blood meal.
- Researchers have focused on early-phase transmission efficiency in various fleas infected with highly bacteremic blood (≥10 cfu/ml).
- This study specifically looks at Oropsylla montana fleas to find the minimum bacteremia needed for them to acquire and transmit Y. pestis, discovering that they can get infected from lower concentrations but only transmit when fed highly bacteremic blood.
Article Abstract
Unblocked fleas can transmit Yersinia pestis, the bacterium that causes plague, shortly (≤4 d) after taking an infectious bloodmeal. Investigators have measured so-called early-phase transmission (EPT) efficiency in various fleas following infection with highly bacteremic blood (≥10cfu/ml). To date, no one has determined the lower limit of bacteremia required for fleas to acquire and transmit infection by EPT, though knowing this threshold is central to determining the length of time a host may be infectious to feeding fleas. Here, we evaluate the ability of Oropsylla montana (Baker) to acquire and transmit Y. pestis after feeding on blood containing 10 to 10cfu/ml. We evaluated the resulting infection prevalence, bacterial loads, and transmission efficiency within the early-phase time period at 1 d postinfection. Fleas acquired infection from bacteremic blood across a wide range of concentrations, but transmission was observed only when fleas ingested highly bacteremic blood.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555412 | PMC |
| http://dx.doi.org/10.1093/jme/tjw004 | DOI Listing |
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