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Science
January 2025
College of Science and Engineering, Flinders University, Bedford Park, South Australia, Australia.
Identifying what drove the late Pleistocene megafaunal extinctions on the continents remains one of the most contested topics in historical science. This is especially so in Australia, which lost 90% of its large species by 40,000 years ago, more than half of them kangaroos. Determining causation has been obstructed by a poor understanding of their ecology.
View Article and Find Full Text PDFBackground: The importance of detecting amyloid β (Aβ) in the early stages of Alzheimer's disease has markedly increased following the approval of Lecanemab, a disease-modifying drug. MRI is a non-invasive and less expensive rather than amyloid PET as gold standard for Aβ biomarker, but its clinical ability to detect Aβ has not been demonstrated. MRI phase information reflects paramagnetic substance including iron associated with Aβ aggregation.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Centre for Brain Research (CBR), Indian Institute of Science, Bengaluru, Karnataka, India.
Background: Alzheimer's disease is a progressive neurodegenerative disorder that mainly affects the brain resulting gradual decline in a cognitive function, memory impairment, alterations in behavior, potentially resulting in the inability to engage in a conversation and react to the surroundings. Corpus callosum (CC) is the principal white fabric matter present in the center of the brain that connects the left and right cerebral hemispheres. Neurodegenerative diseases can impact the size and structure of the CC, leading to its atrophy and dysfunction.
View Article and Find Full Text PDFCompr Rev Food Sci Food Saf
January 2025
Department of Food Science, University of Massachusetts Amherst, Amherst, Massachusetts, USA.
The demand for meat alternatives based on ingredients sourced from nonanimal materials with equivalent quality of muscle tissue is increasing. As more consumers switch to meat alternatives, a growing body of research has investigated the tenderness and related texture attributes in plant-based meats to increase consumer acceptance. A deeper understanding of tenderness including the differences and similarities between meat and meat alternatives is crucial to developing products that meet consumer expectations, as it directly influences consumer acceptance.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Technology and Applied Sciences, Muscat, Muscat, Oman.
Background: Recent breakthroughs in Quantum Calculus (QC) have given new opportunities for texture analysis. Motivated by QC, QELBP examines subtle variations in grayscale within MRI, which may provide early signs of textural changes associated with AD.
Method: 13500 images were extracted from 150 images (90 slices/patient).
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