We report a retrospective case study of the use of clomethiazole for treatment of non-convulsive status epilepticus in a patient not responding to benzodiazepines, illustrated by EEG and video. Clomethiazole can be considered as a safe oral option for management of non-convulsive status epilepticus when conventional treatment has failed. [Published with video sequences online].
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1684/epd.2016.0795 | DOI Listing |
Epilepsy Behav
March 2025
Department of Pediatrics, Division of Child Neurology, Ege University Medical Faculty, Turkey. Electronic address:
Background: Various scoring models have been developed to predict outcomes in pediatric status epilepticus (SE) OBJECTIVES: To compare a set of scoring models for predictivity of outcome characteristics in a single-center pediatric SE cohort.
Patients And Methods: Three SE scoring models (STEPSS, mSTEPSS, and END-IT) were retrospectively evaluated for outcome characteristics in a cohort including 240 children. The areas under curves (AUC) were calculated for the models: short-term outcome with in-hospital mortality, progression to refractory / super-refractory SE, poor outcome at hospital discharge with modified Rankin scale (mRS), and long-term functional outcome with the scores of pediatric overall performance category (POPC) scale at 2-years of follow-up.
Cureus
January 2025
Institute of Neurosciences, Favaloro Foundation University Hospital, Buenos Aires, ARG.
Background Liver transplantation (LT) is a life-saving intervention for end-stage liver disease; however, postoperative complications, particularly neurological issues such as seizures, pose significant challenges. This study aims to identify perioperative factors associated with seizures following LT and develop a predictive risk model. By recognizing these in-hospital risk factors, clinicians may tailor perioperative management to mitigate seizure risk and improve neurological outcomes.
View Article and Find Full Text PDFCureus
January 2025
Neurology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, JPN.
An 81-year-old man was brought to our hospital with tonic-clonic seizures and a gradual progression of cognitive dysfunction. Four months prior, he experienced transient episodes of stiffness and unresponsiveness. One month later, the patient began to exhibit disorientation to time and place.
View Article and Find Full Text PDFEpileptic Disord
February 2025
Department of Neurology, Umraniye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Objective: To investigate the role, frequency, and pattern of signal changes in cranial MRI associated with status epilepticus (SE) and their correlation with EEG and clinical findings in patients with large lesions, such as tumors, strokes, or major space-occupying anomalies.
Methods: This retrospective cohort study included 44 patients diagnosed with SE between January 2013 and June 2019. Data on demographic and clinical characteristics, seizure semiology, SE features (type and prognosis), and EEG and MRI findings were collected from hospital records.
Pract Neurol
February 2025
Unidade Local de Saude do Estuario do Tejo, Vila Franca de Xira, Portugal.
The most common ictal psychiatric symptom is fear, followed by ictal depression, and least commonly ictal psychosis. A 44-year-old man with poststroke focal epilepsy developed new-onset behavioural change, disorientation, hallucinations and delusions, persisting for several months before medical evaluation. He was agitated, disorientated, with impaired memory and disorganised thinking, but had no minor epileptic motor signs.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!