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The Expression of Proteases and the Oligopeptide Transporter in the Yolk Sac Membrane, Proventriculus, and Small Intestine During the Development of Embryo.
Biology (Basel)
November 2024
Department of Biology and Biotechnology, Faculty of Science, Hashemite University, P.O. Box 330127, Zarqa 13133, Jordan.
The role of the yolk sac membrane (YSM) and digestive tract in the processing of egg yolk proteins during embryogenesis is unexplored in the duck . Here, we investigated in the duck embryo the function of the YSM, proventriculus, and small intestine in protein digestion and uptake. We tested the expression of aminopeptidase N () and the oligopeptide transporter as well as the expression of cathepsin B () and cathepsin D () lysosomal genes in the YSM during incubation days 12, 14, 16-18, 20, 22, 24, 26, and 28 (the day of hatch).
View Article and Find Full Text PDFA rare case of huge intracranial yolk sac tumor presenting as an orbital mass in an infant: case report and literature review.
Discov Oncol
December 2024
Department of Radiology, Addis Ababa University, Addis Ababa, Ethiopia.
Primary intracranial yolk sac tumor (YST) with orbital involvement is an exceedingly rare extragonadal germ cell tumor, with only a limited number of cases reported in the literature. Clinically, primary intracranial yolk sac tumor with orbital involvement may present with symptoms that mimic more common benign or malignant orbital disorders in children, potentially leading to diagnostic delays that can adversely impact survival. Diagnostic imaging modalities, including computed tomography (CT) and magnetic resonance imaging (MRI), are instrumental for assessing the tumor's size, precise localization, and extent.
View Article and Find Full Text PDF[Primary uterine hepatoid adenocarcinoma: Clinicopathological analysis of 2 cases and literature review].
Beijing Da Xue Xue Bao Yi Xue Ban
December 2024
Department of Pathology, Fujian Provincial Hospital, Provincial Clinical Medical College of Fujian Medical University, Fuzhou 350001, China.
Primary hepatoid adenocarcinoma (HAC) of the uterus is a particular tumour that bears high similarity to hepatocellular carcinoma histologically, and may easily be misdiagnosed because it is rare if you don' t remember it. In this report, we describe two cases of alpha-fetoprotein (AFP)-producing HAC of the uterus. Case 1 was a 69-year-old postmenopausal woman who was presented to the hospital for a medical examination.
View Article and Find Full Text PDFImmunomodulatory Effects of Modified Colostrum, Whey, and Their Combination With Other Natural Products: Effects on Natural Killer Cells.
Curr Ther Res Clin Exp
June 2024
Division of Clinical Pharmacology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Objectives: Natural killer (NK) cells are important immune system effector cells providing innate defenses against intracellular infections, including viral infections, immune surveillance, and cancer immunoediting. The primary purpose of this study was to investigate whether modified ultra-filtrated colostrum (UC) and hydrolyzed whey (W) products or their combinations with other natural products with reported immunomodulatory properties will stimulate NK cell cytotoxic activity by activation of granzyme B and IFN-γ production.
Methods: The ability of study products to stimulate the cytotoxic activity of human-purified CD56 NK cells and the production of granzyme B and IFN-γ by activated NK cells was evaluated in the cytotoxic assay.
Semen extender triggers a mild physiological inflammatory response in the uterus without disrupting sperm-uterine immune crosstalk in vitro in cattle.
J Reprod Dev
December 2024
Global Agromedicine Research Center (GAMRC), Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan.
Artificial insemination (AI) in cattle involves introducing frozen-thawed sperm, a minimal amount of seminal plasma, and a significant volume of semen extender (SE) into the uterus. Previous studies have demonstrated that sperm interacts with bovine endometrial epithelia via TLR 2/1, triggering a weak inflammatory response to clear the endometrium. This study investigated the impact of the major component of the insemination dose, egg yolk-based SE, on the uterine immune response in vitro.
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