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Xeroform Stick-Down Dressing: A Novel Treatment for Pediatric Partial-Thickness Burns.
Ann Plast Surg
April 2024
From the Division of Plastic and Reconstructive Surgery, University of Massachusetts Chan Medical School, Worcester, MA.
Background: Burns traditionally require frequent, painful dressing changes to minimize infection risk and promote wound healing. To improve care for our pediatric population, our institution adapted a skin graft donor site dressing into a "stick-down" burn dressing consisting of a one-time application of bacitracin and 3% bismuth tribromophenate/vaseline impregnated gauze (Xeroform) that adheres to the burn and peels off as new epithelialized skin forms. The goal of which is to minimize dressing change frequency and patient discomfort in a cost-effective, widely available manner.
View Article and Find Full Text PDFPharmacognostic characterization, wound healing and toxicity assessment of the stem bark of Hutch (Leguminosae).
Heliyon
November 2023
Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
is widely used in traditional medicine to stop bleeding gums and treat wounds. This study was undertaken to assess the wound healing activity and toxicity profile of the stem bark methanol extract of (XES). Wound healing activity was determined by the dermal excision model in rats.
View Article and Find Full Text PDFSulfadiazine analogs: anti-Toxoplasma in vitro study of sulfonamide triazoles.
Parasitol Res
October 2023
Department of Parasitology, Medical Research Institute, Alexandria University, Alexandria, 21561, Egypt.
Article Synopsis
- * The newly synthesized compounds displayed significantly higher anti-Toxoplasma activity than sulfadiazine, with lower inhibitory concentrations and favorable selectivity indices, indicating their potential as better treatment options.
- * Notably, the amino derivatives (specifically 3(d-f)) caused observable and severe morphological changes in both extracellular and intracellular tachyzoites, with compound 3f showing the strongest activity against the parasite.
Stability study of selected veterinary drug residues spiked into extracts from different food commodities.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
September 2023
ANSES Fougeres Laboratory, French National Agency for Food, Environment and Occupational Health & Safety, French and European Union Reference Laboratory for Veterinary Medicinal Product Residues and Pharmacologically Active Dye Residues in Food, Fougères, France.
Analyte stability is more commonly a confounding factor in analytical chemistry than many analysts recognize. In this study, we assessed the stability of 31 common veterinary drugs in water and final extracts of bovine (milk and kidney/liver) and chicken (muscle and egg) matrices. Two different sample preparation methods were evaluated for one-month storage of the final extracts at typical room, refrigerator, and freezer temperatures.
View Article and Find Full Text PDFBioinspired gelatin based sticky hydrogel for diverse surfaces in burn wound care.
Sci Rep
August 2022
School of Biotechnology, National Institute of Technology Calicut, Kozhikode, India.
Proper burn wound management considers patient's compliance and provides an environment to accelerate wound closure. Sticky hydrogels are conducive to wound management. They can act as a preventive infection patch with controlled drug delivery and diverse surface adherence.
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