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Xeroderma Pigmentosum: Part Two: Treatment of Skin Tumors with Topical Podophyllin 25% in Benzoin.
Skinmed
November 2023
Department of Dermatology and Pathology, Immunology, and Laboratory Medicine, Rutgers-New Jersey Medical School, Newark, NJ;
Xeroderma pigmentosum (XP) is a rare autosomal recessive disease; relatively mild XP patients are sometimes designated as having pigmented xerodermoid or xerodermoid pigmentosum (XP-V), a variant of XP. It is commonly associated with many long-standing skin conditions and tumors, including malignancies, management of which is necessary to prevent the progress of the disease. The objective of the study was to evaluate an innovative therapeutic treatment, beyond surgery, surgical excision, cryotherapy, electrocautery and curettage, or Mohs surgery, for the management of skin tumors in XP.
View Article and Find Full Text PDFXeroderma Pigmentosum: Novel Prophylactic and Therapeutic Approaches. Part One: Topical Zinc Sulfate 25% and Heat Dermabrasion plus Topical Trichloroacetic Acid.
Skinmed
November 2023
Departments of Dermatology and Pathology, Immunology, and Laboratory Medicine, Rutgers-New Jersey Medical School, Newark, NJ;
Xeroderma pigmentosum (XP) is a rare autosomal recessive disease; relatively mild XP patients are sometimes designated as having pigmented xerodermoid or xerodermoid pigmentosum (XP-V), a variant of XP. It is commonly associated with many long-standing skin conditions and tumors, including malignancies, management of which is necessary to prevent the progress of the disease. The objective of the study was to report the use of a number of innovative therapeutic and prophylactic treatments, beyond surgery, such as topical 5-fluorouracil, topical imiquimod, other topical immunomodulators, or photodynamic therapy, in treating skin eruptions and their complications in XP patients.
View Article and Find Full Text PDFPigmented Xerodermoid.
Indian Pediatr
January 2016
Department of Dermatology, Katihar Medical College, Bihar and #Department of Pediatrics, SMS Medical College, Jaipur, India.
Pigmented xerodermoid.
Indian J Dermatol Venereol Leprol
July 2007
Department of Skin and STD, Fr. Muller's Medical College, Kankanady, Mangalore-575 002, India.
An 18-year-old female who presented with features suggestive of pigmented xerodermoid is reported.
View Article and Find Full Text PDFPigmented xerodermoid--report of three cases.
Indian J Dermatol Venereol Leprol
March 2006
Department of Dermatology, Vivekananda Institute of Medical Sciences and Ramakrishna Mission Seva Pratisthan Hospital and 99, Sarat Bose Road, Kolkata--700 026, India.
Pigmented xerodermoid, a rare genodermatosis, presents with clinical features and pathology similar to xeroderma pigmentosum, but at a later age. DNA repair replication is normal, but there is total depression of DNA synthesis after exposure to UV radiation. Two siblings in their teens and a man in his thirties with features of pigmented xerodermoid, e.
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