AI Article Synopsis
- Radiotherapy has a long history in treating skin cancers, but its use for non-melanoma cases is debated, often depending on tumor type and surgical options.
- Technological advancements in radiotherapy have reduced side effects and improved targeting, making it a safer option than older techniques.
- This systematic review aims to clarify when radiotherapy is appropriate for non-melanoma skin cancers and suggests optimal practices based on tumor characteristics and patient safety considerations.
Article Abstract
Radiotherapy (RT) has been used for the treatment of skin cancers since very early after the discovery of X-rays. Indications for radiotherapy in non-melanoma cancers are controversial, and are usually decided according to the tumor type and the possibility of curing the patient with surgery. The introduction of sophisticated surgery techniques and the information of the general population on potential late radiation-induced toxicity and carcinogenesis have led to limiting radiation indications in the dermatologist community. However, radiotherapy has undergone considerable development, including technological advances, to enable limiting doses to the organs at risk. Thus, side effects due to high doses and/or the use of old radiotherapy (RT) techniques have been significantly decreased. In this systematic review we aim to discuss indications of radiotherapy in non-melanoma skin cancers and focus on new advances that may lead to rehabilitating this treatment option according to the tumor's radiosensitivity and the clinical benefit/risk ratio. Finally, for each type of cancer, we suggest "the best RT practice".
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| http://dx.doi.org/10.1016/j.critrevonc.2016.01.001 | DOI Listing |
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