AI Article Synopsis

  • This study aimed to analyze the effects of local steroid injections on neuropathic symptoms in patients with carpal tunnel syndrome (CTS), an area not previously explored in detail.
  • Forty-one patients between 22-65 years old, diagnosed with CTS and showing neuropathic symptoms, were treated with steroid injections, and their symptoms were evaluated before and two months after the treatment using specific pain questionnaires and nerve conduction studies.
  • Results indicated that the steroid injections improved both clinical symptoms and nerve conduction results, but the severity of the nerve condition (as measured electrophysiologically) did not correlate with the pain questionnaire scores, suggesting that treatment for neuropathic pain should be independent of these electrophysi

Article Abstract

Background/purpose: The purpose of this study was to evaluate the neuropathic symptoms after local steroid injection in CTS. Since 2001, neuropathic pain scales have been used in the assessment and follow-up of neuropathic pain. DN4 and LANSS pain questionnaires have been applied to groups, mostly consisted of radiculopathy and polyneuropathy cases, before and after various treatments and the results have been compared with the electrophysiologic findings. However to our knowledge there is yet no such study focusing on neuropathic complaints and the relationship between neuropathic pain and electrophysiological findings before and after local corticosteroid injection.

Methods: Forty-one patients aged 22-65 years and diagnosed with carpal tunnel syndrome by nerve conduction studies who were also found to have neuropathic symptoms were included in the study. All patients received local steroid injection into the carpal tunnel while the questionnaires and nerve conduction studies were performed before and 2 months after the injection.

Results: Local steroid injection was found effective on clinical and electrophysiologic parameters as well as on DN4 and LANSS scores in CTS patients (p< 0.05). Electrophysiologic severity exhibited no statistically significant relationship with DN4 and LANSS scores, before and after treatment (p> 0.05).

Conclusion: These findings suggests that the treatment of neuropathic complaints should be planned independently from the electrophysiologic findings and minimally invasive local steroid injection appears to be effective with regard to clinical and electrophysiologic aspects in CTS patients with neuropathic complaints.

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Source
http://dx.doi.org/10.3233/BMR-160660DOI Listing

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