Previous studies suggest that altered corneal temperature may be a feature of schizophrenia, but the association between major depressive disorder (MDD) and corneal temperature has yet to be assessed. The aim of this study is to investigate whether eye temperature is different among MDD patients than among healthy individuals. We used a thermographic camera to measure and compare the temperature profile across the corneas of 16 patients with MDD and 16 age- and sex-matched healthy subjects. We found that the average corneal temperature between the two groups did not differ statistically, although clinical severity correlated positively with right corneal temperature. Corneal temperature may be an indicator of clinical severity in psychiatric disorders, including depression.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1117/1.JBO.21.2.026001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Low-temperature vacuum evaporation as a novel dehydration process for the long-term preservation of transplantable human corneal tissue.
Cell Tissue Bank
January 2025
Academic Ophthalmology, Mental Health and Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, UK.
Globally there is a shortage of available donor corneas with only 1 cornea available for every 70 needed. A large limitation to corneal transplant surgery is access to quality donor tissue due to inadequate eye donation services and infrastructure in many countries, compounded by the fact that there are few available long-term storage solutions for effectively preserving spare donor corneas collected in countries with a surplus. In this study, we describe a novel technology termed low-temperature vacuum evaporation (LTVE) that can effectively dry-preserve surplus donor corneal tissue, allowing it to be stored for approximately 5 years, shipped at room temperature, and stored on hospital shelves before rehydration prior to ophthalmic surgery.
View Article and Find Full Text PDFModelling the thermal effects of stimulus airflow from the Dolphin aesthesiometer on a model eye surface.
Ophthalmic Physiol Opt
December 2024
School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, Canada.
Purpose: To assess the ability of the Dolphin air-pulse aesthesiometer to present multiple stimuli, which are separated temporally (in sequence) or spatially (simultaneously).
Methods: Two studies were performed to explore the cooling effects induced by double air-puff stimuli generated by a novel aesthesiometer composed of two micro-blower integrated units. The stimuli were delivered sequentially or simultaneously at the same or different spatial locations to an in vitro eye model monitored using thermography.
Stability enhancement of Amphotericin B using 3D printed biomimetic polymeric corneal patch to treat fungal infections.
Int J Pharm
December 2024
Translational Pharmaceutics Research Laboratory (TPRL), Department of Pharmacy, Birla Institute of Technology and Sciences (BITS), Pilani, Hyderabad Campus, Hyderabad, Telangana 500078, India. Electronic address:
Amphotericin B eye drops (reconstituted from lyophilized Amphotericin B formulation indicated for intravenous use) is used off-label for fungal keratitis. However, the reconstituted formulation is stable only for a week, even after refrigeration. Moreover, a high dosing frequency makes it an inconvenient treatment practice.
View Article and Find Full Text PDFDevelopment of lacosamide-loaded in-situ gels through experimental design for evaluation of ocular irritation in vitro and in vivo.
J Pharm Sci
December 2024
Faculty of Pharmacy, Süleyman Demirel University, Isparta, Türkiye.
Lacosamide (LCM) selectively increases the slow inactivation of voltage-gated sodium channels (VGSCs) and is a N-methyl d-aspartate acid (NMDA) receptor glycine site antagonist. Therefore, it can be used in dryness-related hyperexcitability of corneal cold receptor nerve terminals. Ocular in-situ gels remain in liquid form until they reach the target site, where they undergo a sol-gel transformation in response to specific stimuli.
View Article and Find Full Text PDFEffects of ambient atmospheric pressure on intraocular pressure measured using a Goldman applanation tonometer in normal eyes under ordinary conditions.
Graefes Arch Clin Exp Ophthalmol
December 2024
Kaiya Eye Clinic, Hamamatsu, Shizuoka, Japan.
Purpose: Little is known about the effects of ambient atmospheric pressure (AP) on intraocular pressure (IOP) under ordinary conditions. This study aimed to investigate the effects of AP on Goldmann applanation tonometer-measured IOP (GAT-IOP) in normal eyes under everyday atmospheric conditions adjusting for effects of possible confounding factors including other climatic factors.
Methods: Data obtained from 2,431 normal healthy eyes of 2,431 subjects (mean age: 56.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!