Background: The best treatment for advanced tongue tumors remains controversial. Total glossectomy with laryngeal preservation is considered a feasible option, despite its morbidity.
Methods: A retrospective analysis of 12 total glossectomies with laryngeal preservation was performed in order to assess the available reconstruction techniques and analyze survival and functional outcomes.
Results: One-year overall survival (OS) and disease-free survival (DFS) rates were 58.3% and 33.3%, respectively, both dropping to 25% after 3 years. Permanent gastrostomy was necessary in 10 patients, although videofluoroscopy revealed adequate tolerance to liquids. Speech intelligibility was satisfactory in 50% of the patients and severely impaired in the remaining 50%.
Conclusion: Laryngeal preservation in the context of advanced tumors of the tongue without supraglottic invasion carried similar oncologic results to total glossectomy with laryngectomy, but offers a better phonatory function. However, it is usually associated with a higher gastrostomy dependency ratio. A scrupulous selection of candidates is mandatory. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2004-E2010, 2016.
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http://dx.doi.org/10.1002/hed.24369 | DOI Listing |
BMJ Open
December 2024
Department of Anesthesiology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital, Shanghai, China
Objectives: This study aimed to evaluate the predictive abilities of the 5-item modified Frailty Index (5-mFI), Prognostic Nutrition Index (PNI), and their combination in older adult patients undergoing oral cancer resection and free flap reconstruction.
Design: Retrospective cohort study.
Setting: Secondary care involving multiple centres treating older adult patients for oral cancer.
Eur Arch Otorhinolaryngol
December 2024
All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India.
Oral Maxillofac Surg
December 2024
Colorectal Research Center, Department of Radiation Oncology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Introduction: This study aimed to explore the predictive and prognostic value of tumor-stromal ratio (TSR) and tumor budding (TB) in the recurrence and outcome of patients with Oral tongue squamous cell carcinoma (OTSCC).
Methods: All patients with OTSCC who underwent glossectomy with or without neck dissection in a tertiary center between 2010 and 2020 were included. The pathology slides of all patients were reviewed by a consulting pathologist.
J Prosthet Dent
November 2024
Professor, Department of Prosthodontics, Faculty of Dentistry, Cairo University, Cairo, Egypt.
Statement Of Problem: Studies on the significance of intensity on speech production with a tongue prosthesis are lacking, despite this being an important criterion in speech production in patients with total glossectomy.
Purpose: The purpose of this cross-over clinical study was to assess acoustic signal intensity and frequency in patients with total glossectomy rehabilitated with mandibular dentures with 2 different attachment designs for the tongue prosthesis.
Material And Methods: Seven participants initially received a mandibular denture with a tongue prosthesis attached using an acrylic resin plate.
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