AI Article Synopsis
- The study examined ophthalmic abnormalities in 121 children with congenital hypothyroidism, finding that 40.4% had eye issues.
- Among those with eye issues, a majority (79.5%) had significant refractive errors, and 32.6% had strabismus.
- Additionally, 74.3% of the children had systemic abnormalities, with common issues including congenital heart defects and neurologic problems, highlighting the need for regular eye exams starting at diagnosis.
Article Abstract
Purpose: To evaluate the frequencies of ophthalmic abnormalities in children with congenital hypothyroidism.
Methods: A total of 121 patients with a history of congenital hypothyroidism, aged 1 to 216 months, were included in the study. The initial ophthalmological examinations and demographic data of patients who were examined between April 2013 and April 2015 were retrospectively reviewed. Accompanying systemic abnormalities were also noted.
Results: Ophthalmic pathology was determined in 40.4% (49 of 121) of patients with congenital hypothyroidism, of which 79.5% (39 of 49) had significant refractive errors and 32.6% (16 of 49) had strabismus. Systemic abnormalities were observed in 74.3% (90 of 121) of the children, among which 47.1% (57 of 121) were congenital heart defects and 38.0% (46 of 121) were neurologic abnormalities. A high prevalence of Down syndrome (17.3%; 21 of 121) and atopic dermatitis (8.2%; 10 of 121) was detected among patients with congenital hypothyroidism.
Conclusions: In addition to many associated systemic abnormalities, ophthalmic pathologies may also occur in children with congenital hypothyroidism. Thus, routine ophthalmological examination is recommended for these children, starting from the time of initial diagnosis.
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| http://dx.doi.org/10.3928/01913913-20160113-06 | DOI Listing |
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