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| http://dx.doi.org/10.3978/j.issn.2224-4336.2012.12.01 | DOI Listing |
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Hierarchical Multi-Label Classification With Gene-Environment Interactions in Disease Modeling.
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In biomedical studies, gene-environment (G-E) interactions have been demonstrated to have important implications for analyzing disease outcomes beyond the main G and main E effects. Many approaches have been developed for G-E interaction analysis, yielding important findings. However, hierarchical multi-label classification, which provides insightful information on disease outcomes, remains unexplored in G-E analysis literature.
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