Recently, due to spread of dangerous and especially dangerous infections much attention is given to development of complex approaches to their prophylaxis and therapy. Data on use of immune modulators, cytokines, probiotics, preparations of plant origin for non-specific prophylaxis of especially dangerous infections are analyzed in the review, and expediency of their combined use with specific and emergency prophlaxis of these diseases is evaluated.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Cross-sectional evaluation of medical reversals among National Institute of Health guideline practices implemented during the COVID-19 pandemic: how often did experts err in a time of crisis?
BMJ Open
December 2024
Department of Medicine, The University of Chicago, Chicago, Illinois, USA.
Objective: The COVID-19 pandemic required the rapid and often widespread implementation of medical practices without robust data. Many of these practices have since been tested in large, randomised trials and were found to be in error. We sought to identify incorrect recommendations, or reversals, among National Institute of Health COVID-19 guidelines and Food and Drug Administration (FDA) approvals and authorisations.
View Article and Find Full Text PDFSuper-hydrophilic and super-lubricating Zwitterionic hydrogel coatings coupled with polyurethane to reduce postoperative dura mater adhesions and infections.
Acta Biomater
January 2025
Department of Polymer Science and Engineering, Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, PR China; Frontiers Science Center for Synthetic Biology, Key Laboratory of Systems Bioengineering(MOE), Tianjin University, Tianjin 300072, PR China. Electronic address:
The dura trauma or large defects due to neurosurgical procedures can result in potential complications. Dural replacements have proven effective to reduce the risk of seizures, meningitis, cerebrospinal fluid leakage, cerebral herniation, and infection. Although various artificial dural patches have been developed, addressing iatrogenic infections and cerebral adhesions resulting from patches implantation remains a challenge.
View Article and Find Full Text PDF[Diphtheria-tetanus-pertussis vaccine mortality].
Ugeskr Laeger
December 2024
Mikkelborg Alle, Hørsholm.
Although the diphtheria-tetanus-pertussis (DTP) vaccine is lifesaving through decades, it has been voiced that the vaccine is associated with 50% increase in mortality, an alleged negative non-specific vaccine effect prone to girls. Post hoc analyses of historical observational data supporting the hypothesis of the DTP vaccine having detrimental effects have never been replicated in low- or high-income countries. An RCT in Guinea-Bissau found fewer deaths with DTP vaccine than without.
View Article and Find Full Text PDFClinical and Epidemiologic Features of Infection Among Adults Hospitalized with Community-acquired Pneumonia.
Int J Med Sci
December 2024
Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Article Synopsis
- - The EPIC study analyzed data from 2,272 adults hospitalized for pneumonia to understand the prevalence of Mycoplasma pneumoniae (Mp) using PCR testing on throat swabs from 2010 to 2012.
- - Only 43 patients (1.8%) tested positive for Mp, primarily affecting younger adults (median age: 45), with some experiencing severe cases leading to ICU admissions, but no in-hospital deaths were reported.
- - Factors linked to higher Mp detection included being younger and having certain radiographic findings, indicating the need for better testing methods to improve diagnosis and treatment options for pneumonia patients.
A green, versatile, and facile strategy for anti-biofouling surface with ultra-high graft density polyethylene glycol.
J Nanobiotechnology
December 2024
Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou Key Laboratory of Perioperative Medicine, Wenzhou, 325001, Zhejiang, China.
Implantable catheters are susceptible to severe complications due to non-specific protein adhesion on their surfaces. Polyethylene glycol (PEG) coatings, the gold standard for resistance to non-specific protein adhesion, present a challenge in achieving high-density grafting, which significantly restricts their use as anti-biofouling coatings. Herein, we exploited the strong interaction between polyphenols (PCs) and polycations (K6-PEG) to graft PEG onto the surface of PC-Cu (A network of metal polyphenols composed of proanthocyanidins and metal copper ions, with expectation for the coating with excellent resistance to non-specific protein adhesion (PC-Cu@K6-PEG).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!