FDG PET/CT Findings in Abdominal Fat Necrosis After Treatment for Lymphoma.

Clin Nucl Med

From the Departments of *Nuclear Medicine, †Hematology, and ‡Histopathology, Hospices Civils de Lyon, Université de Lyon 1, Lyon, France.

Published: May 2016

AI Article Synopsis

  • FDG PET/CT is now recognized as an effective tool for evaluating treatment responses in patients with non-Hodgkin lymphoma.
  • A case study describes a 62-year-old man with stage III diffuse large B-cell lymphoma who underwent FDG PET/CT scans.
  • The interim scan showed complete metabolic and morphological response in lymph nodes, but also detected abnormal uptake in the abdomen, leading to a biopsy that revealed diffuse fat necrosis rather than cancer.

Article Abstract

FDG PET/CT is now validated in non-Hodgkin lymphoma for response assessment in interim and posttreatment lymphoma. We report the case of a 62-year-old man followed by FDG PET/CT for a diffuse large B-cell lymphoma, with initial stage III. The interim FDG PET/CT examination concluded in complete metabolic and morphological response of subdiaphragmatic lymphadenopathy but a persistent abnormal subdiaphragmatic uptake (SUVmax at 9 and Deauville 5-point scale at 5). Therefore, an abdominal biopsy of the corresponding nodules was conducted with a final diagnosis of diffuse fat necrosis.

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http://dx.doi.org/10.1097/RLU.0000000000001111DOI Listing

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