Five groups of 19 subjects made ratings on 11 personality trait scales of overlapping subsets of 59 artificial stimulus persons who were described by one to five personality trait adjectives. The data were analyzed per group of subjects (blockwise) and per type of stimulus person (questionnaire-wise) by means of three-mode principal component analyses. This yielded highly similar structures for the scales, and in the blockwise analyses, for the stimulus persons. This similarity was substantiated by external three-mode analyses, which showed that all stimulus persons can be mapped into one overall configuration. In all analyses it was found that differences between subjects consisted of differences in extremity of judgment, which suggests the operation of response style.
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Sci Rep
January 2025
Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4515 McKinley Ave., St. Louis, MO, 63110, USA.
Functional magnetic resonance imaging (fMRI) has dramatically advanced non-invasive human brain mapping and decoding. Functional near-infrared spectroscopy (fNIRS) and high-density diffuse optical tomography (HD-DOT) non-invasively measure blood oxygen fluctuations related to brain activity, like fMRI, at the brain surface, using more-lightweight equipment that circumvents ergonomic and logistical limitations of fMRI. HD-DOT grids have smaller inter-optode spacing (~ 13 mm) than sparse fNIRS (~ 30 mm) and therefore provide higher image quality, with spatial resolution ~ 1/2 that of fMRI, when using the several source-detector distances (13-40 mm) afforded by the HD-DOT grid.
View Article and Find Full Text PDFCancer Lett
January 2025
Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, 200025, China. Electronic address:
Neutrophils are pivotal in the immune system and have been recognized as significant contributors to cancer development and progression. These cells undergo metabolic reprogramming in response to various stimulus, including infections, diseases, and the tumor microenvironment (TME). Under normal conditions, neutrophils primarily rely on aerobic glucose metabolism for energy production.
View Article and Find Full Text PDFJ Electromyogr Kinesiol
January 2025
Centro Polifunzionale di Scienze Motorie, Università degli Studi di Genova, Genoa, Italy; Department of Experimental Medicine, Section of Human Physiology, Università degli Studi di Genova, Genoa, Italy.
This study investigated proprioceptive acuity using the conventional joint position reproduction (JPR) task and a modified version, the Dynamic JPR task (D-JPR), during Concentric and Eccentric muscle contractions. Seventeen participants were recruited and received a tactile stimulus indicating the position cue at Initial (INI), Intermediate (INT), and Final (FIN) phases of movements, during either the concentric or eccentric phases. After the movement, they replicated the position where they received the stimulus.
View Article and Find Full Text PDFArthritis Res Ther
January 2025
Xin'an Medicine Research Center, the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), No 2, West Zheshan Road, Wuhu, Anhui, 241000, China.
Background: Metabolism alteration is a common complication of rheumatic arthritis (RA). This work investigated the reason behind RA-caused triglyceride (TG) changes.
Methods: Fresh RA patients' whole blood was transfused into NOD-SCID mice.
Eur J Pain
March 2025
Department of Life Sciences, South Kensington, Imperial College London, London, UK.
Background: Healthy individuals demonstrate considerable heterogeneity upon dynamic quantitative sensory testing assessment of endogenous pain modulatory mechanisms. For those who stratify into a 'pro-nociceptive profile' cohort, consisting of inefficient conditioned pain modulation (CPM) and elevated temporal summation of pain (TSP), the optimal approach for balancing the net output of pain modulatory processes towards anti-nociception remains unresolved. In this translational healthy human and rat study, we examined whether descending modulation countered spinal amplification during concurrent application of a CPM and TSP paradigm alongside pupillometry since pontine activity was previously linked to functionality of endogenous pain modulatory mechanisms and pupil dilation.
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