Flight medical expertise (FME) in military aviation is one of the most important areas of medical support of flight crews manning, maintaining of aircrew health and flight safety. The authors analyse the main stages of development of this area of medical practice. The priority in creation of FME system belongs to our country. Domestic scientists, prominent organizers of military medicine and a large group of aviation physicians developed organizational and methodological basis for studying different impacts of flight factors on the health of flight personnel, development of criteria for admission to flight operations, principles of organization of the examination, implementation of effective methods of disease diagnosis. At the present stage FME development is determined by the needs of medical, technical and psycho-physiological support of supersonic aircraft, the need to adjust to the requirements of aircrew health, advanced diagnostics of the functional state and the search for means to improve the stability of his body to flight factors. The main principles of the FME remains the complexity of the study of the human body in terms of its professional and individual approach to a medical examination, a thorough clinical, clinical and physiological and psychological examinations, regular medical supervision of the health of flight crews.
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Exp Neurol
January 2025
Traumatic Brain Injury & Metabolomics Department, DRDO, Institute of Nuclear Medicine and Allied Sciences (INMAS), S. K Mazumdar Road, Timarpur, New Delhi 110054, India. Electronic address:
Head trauma from blast exposure is a growing health concern, particularly among active military personnel, and is considered the signature injury of the Gulf War. However, it remains elusive whether fundamental differences exist between blast-related traumatic brain injuries (TBI) and TBI due to other mechanisms. Considering the importance of lipid metabolism associated with neuronal membrane integrity and its compromise during TBI, we sought to find changes in lipidomic profiling during blast or blunt (Stereotaxically Controlled Contusison-SCC)-mediated TBI.
View Article and Find Full Text PDFBackground: Currently there is no way to determine if archived cerebrospinal fluid (CSF) specimens have been properly handled and can be considered suitable for research purposes. Transthyretin (TTR) is abundant in CSF and undergoes a redox reaction that shifts its native proteoform into an S-cysteinylated form. This reaction proceeds spontaneously ex vivo when CSF is thawed, but ceases at storage temperatures of -80°C.
View Article and Find Full Text PDFJ Magn Reson Imaging
January 2025
Department of Radiology, Endeavor Health, Evanston, Illinois, USA.
Background: Luminal and hemodynamic evaluations of the cervical arteries inform the diagnosis and management of patients with cervical arterial disease.
Purpose: To demonstrate a 3D nonenhanced quantitative quiescent interval slice-selective (qQISS) magnetic resonance angiographic (MRA) strategy that provides simultaneous hemodynamic and luminal evaluation of the cervical arteries.
Study Type: Prospective.
J Sep Sci
January 2025
Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, Shijiazhuang, China.
A novel dual-wavelength ultrahigh performance liquid chromatography (UHPLC) fingerprint was established, 56 common peaks were confirmed and attributed to the source of the medicinal materials, and 13 chromatographic peaks of them were identified by UHPLC quadrupole time-of-flight (Q-TOF)-MS/MS and UHPLC-UV method. Furthermore, a simple and sensitive HPLC-quadrupole trap (Q-TRAP)-MS/MS was developed for the simultaneous determination of 16 active components with electrospray ionization (ESI) source switching between positive and negative modes in a single run. The above two methods were successfully applied for the quality evaluation of Guanxinjing capsule (GXJC).
View Article and Find Full Text PDFHealth Sci Rep
January 2025
Division of Descriptive Research Indian Council of Medical Research-Headquarters New Delhi Delhi India.
Background And Aims: In the past decade, unmanned aerial systems (UASs), commonly known as drones, have found applications not only in military and agriculture but also in the transportation of medical supplies.
Purpose: The present study was conducted to assess the practicality of utilizing drones as a mode for the delivery of vaccines to combat the challenges.
Study Design: An exploratory study.
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