To drive its migration through a fibrillar matrix—and thus to spread, invade or metastasize—a cancer cell must exert physical forces. The first visualization of these forces in three dimensions reveals surprising migration dynamics.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861038PMC
http://dx.doi.org/10.1038/nmeth.3744DOI Listing

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