Primary Intracranial Leptomeningeal Melanomatosis.

J Korean Neurosurg Soc

Department of Pathology, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea.

Published: December 2015

Primary intracranial malignant melanoma is a very rare and highly aggressive tumor with poor prognosis. A 66-year-old female patient presented a headache that had been slowly progressing for several months. A large benign pigmented skin lesion was found on her back. A brain MRI showed multiple linear signal changes with branching pattern and strong enhancement in the temporal lobe. The cytological and immunohiostochemical cerebrospinal fluid examination confirmed malignant melanoma. A biopsy confirmed that the pigmented skin lesion on the back and the conjunctiva were benign nevi. We report a case of primary intracranial malignant melanoma and review relevant literatures.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728095PMC
http://dx.doi.org/10.3340/jkns.2015.58.6.554DOI Listing

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