Eosinophilic gastroenteritis is a rare disorder of unknown cause characterized by focal or diffuse eosinophilic infiltration of gastrointestinal tract, especially the stomach and duodenum. Its clinical presentation depends on which segment of gastrointestinal tract is affected and on the depth of eosinophilic infiltration in the affected segment. We present a case of a 35-year-old male with abdominal distention for six months. Laboratory testing revealed elevated eosinophil count and serum immunoglobulin E (IgE) levels. In abdominal tomography, ascites was observed, and eosinophilic infiltration was detected in duodenum biopsy samples, collected during endoscopic examination of upper gastrointestinal system. Clinical and pathologic findings of the patient responded to steroid dramatically. Even though their comorbidity is rare, eosinophilic gastroenteritis should be considered in differential diagnosis of patients with unspecified ascites.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706876 | PMC |
http://dx.doi.org/10.1155/2015/971607 | DOI Listing |
Rev Esp Enferm Dig
January 2025
Aparato Digestivo, Complejo Hospitalario Universitario de A Coruña.
Eosinophilic gastroenteritis is an uncommon, chronic, immune-mediated condition characterized by eosinophilic infiltration that can affect any segment of the gastrointestinal tract. Clinical manifestations depend on the different layers of the intestinal wall affected, which also allows its classification into three subtypes (Klein classification) (1): mucosal, which presents with abdominal pain, diarrhea, or vomiting; muscular, with obstruction or perforation; and serosal, classically with ascites. Diagnosis requires the demonstration of tissue eosinophilia with compatible clinical manifestations, after excluding other causes of eosinophilia.
View Article and Find Full Text PDFArthritis Res Ther
January 2025
Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, the Ministry of Education Key Laboratory, Chinese Academy of Medical Sciences & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, China.
Objective: Severe gastrointestinal lesions are associated with a poor prognosis in eosinophilic granulomatosis with polyangiitis (EGPA). The goal of this study was to develop an effective predictive model for gastrointestinal lesions and to examine clinical patterns, associated factors, treatment, and outcomes of gastrointestinal lesions in EGPA.
Methods: We retrospectively enrolled 165 EGPA patients.
BMC Pediatr
December 2024
Department of Pediatrics, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing312000, China.
Background: Eosinophilic Gastrointestinal Disorders beyond Eosinophilic Esophagitis (non-EoE EGIDs) are chronic rare inflammatory disorders characterized by eosinophilic infiltration of the gastrointestinal (GI) tract.
Case Presentation: We report the first pediatric case of eosinophilic duodenitis (one type of the non-EoE EGIDs) with concomitant pancreatic reaction that was misdiagnosed as acute pancreatitis (AP). A 13-year-old girl was admitted to our hospital for a week of abdominal distension, vomiting, and epigastric pain that worsened recently.
Am J Transl Res
November 2024
Department of Pediatrics, Zhejiang Provincial Integrated Chinese and Western Medicine Hospital Hangzhou 310003, Zhejiang, China.
Eosinophilic gastroenteritis (EGE) is an inflammatory disease characterized by a significant increase in eosinophils. EGE itself is rare, and cases with clinical manifestations of hemorrhagic ascites are even rarer, which undoubtedly increases the risk of misdiagnosis. Given this, this study reports a rare case of pediatric EGE presenting with paroxysmal abdominal pain without apparent cause, accompanied by acute tonsillitis and mesenteric lymphadenitis, suggesting a possible intestinal infection.
View Article and Find Full Text PDFEosinophilic gastroenteritis is characterized by eosinophilic infiltration of the stomach and intestine. It is a rare disorder with bizarre presentations, making it difficult to diagnose and often leading to misdiagnoses. It can present with abdominal pain, diarrhea, vomiting, obstruction, ascites, etc.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!